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Basic information

CohesinDB ID: CDBP00413533

Locus: chr21-15601722-15602750

Data sourse: GSE206145, GSE206145-GSE177045, GSE120943, GSE98367

Cell type: MCF-7, RPE, Monocytes, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,NIPBL,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 56% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 94%, "14_ReprPCWk": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MAFG, FOXA2, NME2, DUX4, FOXA1, ZNF596, ERG, ZNF384, MEN1, DAXX, OTX2, GATA3, STAT3, ZSCAN4, ZNF10, GATA1, TLE3, NR3C1, CEBPB, TEAD1, PIAS1, ESR1, C11orf30, GRHL2, NFKB1, BAF155, AR, GATA6, GATA2, HSF1, NFIL3, TEAD4, ZNF316

Target gene symbol (double-evidenced CRMs): BTG3,USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000155313, ENSG00000154640,

eachgene

Deatailed information for cohesin site CDBP00413533