- Basic information
- CohesinDB ID: CDBP00413539
- Locus: chr21-15616932-15619309
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Data sourse: ENCSR000BLD, ENCSR000BTU, GSE72082, GSE138405, GSE116344, GSE25021, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, GSE68388, GSE138105, ENCSR703TNG, GSE126990, GSE108869, ENCSR000ECS
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Cell type: MCF-7, H1-hESC, RPE, Fibroblast, Hela-Kyoto, RH4, SLK, Ishikawa, HeLa-S3, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
56% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 78%,
"7_Enh": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, SMARCA2, ZNF660, SOX2, MEIS2, FOXA1, HLF, PBX2, ZFHX2, TFAP4, NFIC, CHD7, ATF4, CBFB, ZNF273, TEAD1, ZNF217, ESR1, TP73, USF2, JUN, TCF12, CTCF, EP300, BAF155, MNT, PAX8, SOX4, TEAD4, TFAP2C, NANOG, CHD8, POU5F1, MYCN, TOP2A, CTBP1, SRF, ERG, ZBTB21, MYC, RAD21, PROX1, NKX2-1, GABPA, STAT3, UBN1, NKX3-1, RCOR1, VDR, NR3C1, CEBPB, ZNF750, GRHL2, EBF3, EHF, IRF1, GATA2, FLI1, MRTFB, ZIM3, NCOA2, CEBPA, ZNF335, SIN3A, SMAD3, ERG3, SMARCC1, ZXDC, CREBBP, RUNX2, PBX4, ARNT, NFIB, PBX3, FOXM1, FOS, MED1, PIAS1, USF1, ZHX1, ASH2L, SMC3, STAG1, FOXA2, FOXF1, HOXB13, RELA, JUNB, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, CEBPG, KLF4, NR2F2, ELF3, AR, YAP1, BRD4, JUND, AHR
- Target gene symbol (double-evidenced CRMs): BTG3,USP25
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops