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Basic information

CohesinDB ID: CDBP00413569

Locus: chr21-15726005-15726347

Data sourse: ENCSR703TNG, GSE25021, GSE72082

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: SA1,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 56% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 81%, "14_ReprPCWk": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, SIN3A, XBP1, FOXA1, PBX2, CREBBP, MYC, RAD21, GATA3, SMARCE1, NRIP1, NCOA3, NR2F2, ZNF217, ESR1, PKNOX1, GRHL2, AR, HDAC2, GATA2, CTBP2, AHR

Target gene symbol (double-evidenced CRMs): NRIP1,BTG3,HSPA13,USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000155304, ENSG00000180530, ENSG00000155313, ENSG00000154640,

eachgene

Deatailed information for cohesin site CDBP00413569