- Basic information
- CohesinDB ID: CDBP00413783
- Locus: chr21-16554422-16555230
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Data sourse: GSE206145, ENCSR230ZWH, ENCSR917QNE
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Cell type: RPE, Liver
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 60%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, FOXO1, RUNX1, NANOG, SMC1A, CHD8, FOXA2, TBL1X, POU5F1, MYCN, SOX2, ZFX, POU4F2, WT1, ZBTB48, FOXA1, HOXB13, TWIST1, ERG, YY1, RELA, CREBBP, ETS1, RAD21, PRDM1, ARNT, HIF1A, FOXP2, OTX2, GATA3, PRDM9, GABPA, TAL1, XRCC5, GATA1, PRDM14, HAND2, CSNK2A1, NCOA3, NR2F2, CREB1, TFAP2C, ESR1, JUN, BCL11A, BAF155, SP1, PAX3-FOXO1, AR, GATA2, NOTCH3, E2F1, AHR
- Target gene symbol (double-evidenced CRMs): BTG3,NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000180530,
ENSG00000154640,
- Related loop:
chr21:14975000-15000000~~chr21:16550000-16575000,
chr21:15000000-15025000~~chr21:16550000-16575000,
chr21:16075000-16100000~~chr21:16550000-16575000,
chr21:16175000-16200000~~chr21:16525000-16550000,
chr21:16175000-16200000~~chr21:16550000-16575000,
chr21:16400000-16425000~~chr21:16525000-16550000,
chr21:16450000-16475000~~chr21:16550000-16575000,
chr21:16550000-16575000~~chr21:17450000-17475000,
chr21:16550000-16575000~~chr21:17600000-17625000,