- Basic information
- CohesinDB ID: CDBP00413785
- Locus: chr21-16556680-16557811
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Data sourse: GSE67783, GSE86191, GSE206145, GSE206145-NatGen2015, GSE62063, GSE138105
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Cell type: RPE, Fibroblast, HCT-116, HEK293T, SLK, HSPC, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.922
- Subunit: NIPBL,SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 67%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, AR, CEBPB, OGG1, CEBPA, SP140, XBP1, GRHL3, HIF1A, ZBTB48, OTX2, PHOX2B, CDK9
- Target gene symbol (double-evidenced CRMs): NRIP1,BTG3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000180530,
ENSG00000154640,
- Related loop:
chr21:14975000-15000000~~chr21:16550000-16575000,
chr21:15000000-15025000~~chr21:16550000-16575000,
chr21:16075000-16100000~~chr21:16550000-16575000,
chr21:16081685-16083647~~chr21:16561217-16562728,
chr21:16175000-16200000~~chr21:16550000-16575000,
chr21:16450000-16475000~~chr21:16550000-16575000,
chr21:16550000-16575000~~chr21:17450000-17475000,
chr21:16550000-16575000~~chr21:17600000-17625000,