- Basic information
- CohesinDB ID: CDBP00413786
- Locus: chr21-16561687-16562411
-
Data sourse: ENCSR000BLD, ENCSR000BTU, GSE126990, GSE72082, GSE138405, GSE25021, ENCSR000BLY, ENCSR000BLS, GSE105028, GSE152721, ENCSR000ECE, ENCSR000EDE, GSE68388, GSE116344, GSE106870, GSE50893, GSE145327, GSE97394
-
Cell type: MCF-7, GM2630, H1-hESC, Hela-Kyoto, RH4, Hep-G2, CVB-hiPSC, Ishikawa, HeLa-S3, HUES64, SK-N-SH, HAP1, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.844
- Subunit: SA1,Rad21,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 62%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, CHD8, FOXA2, SOX2, ZNF534, FOXA1, ERG, ZBTB2, JUNB, RUNX2, GR, RAD21, FOXP2, GRHL3, HIF1A, OTX2, GATA3, GABPA, ZNF143, MED1, ARNTL, CSNK2A1, NR3C1, MYOG, KDM5B, ESR1, OCA2, CTCF, SPI1, AR, GATA2, EGLN2, BRD4, E2F1, MAZ, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): NRIP1,BTG3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000180530,
ENSG00000154640,
- Related loop:
chr21:14975000-15000000~~chr21:16550000-16575000,
chr21:15000000-15025000~~chr21:16550000-16575000,
chr21:16075000-16100000~~chr21:16550000-16575000,
chr21:16081685-16083647~~chr21:16561217-16562728,
chr21:16175000-16200000~~chr21:16550000-16575000,
chr21:16450000-16475000~~chr21:16550000-16575000,
chr21:16550000-16575000~~chr21:17450000-17475000,
chr21:16550000-16575000~~chr21:17600000-17625000,