Deatailed information for cohesin site CDBP00413787

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  • Basic information
  • CohesinDB ID: CDBP00413787
  • Locus: chr21-16563033-16564655
  • Data sourse: ENCSR000BLD, ENCSR230ZWH, ENCSR501LQA, GSE126634, ENCSR760NPX, ENCSR150EFU, GSE105028, ENCSR000ECS, ENCSR330ELC, GSE108869, ENCSR000BUC, ENCSR917QNE, GSE165895, ENCSR000BTU, GSE67783, GSE138405, GSE76893, GSE206145-NatGen2015, ENCSR806UKK, GSE138105, GSE130135, GSE116344, ENCSR895JMI, ENCSR193NSH, ENCSR768DOX, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR807WAC, ENCSR495WGO, ENCSR984DZW, GSE97394, ENCSR217ELF, ENCSR853VWZ, ENCSR956LGB, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR537EFT, ENCSR000EDE, GSE68388, GSE83726, GSE126990, ENCSR748MVX
  • Cell type: RPE, H1-hESC, Fibroblast, Hela-Kyoto, RH4, HEK293T, HFFc6, SLK, Ishikawa, A-549, HeLa-S3, HUES64, HSPC, RT-112, Liver, HAP1, HuCC-T1, H9-hESC
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 21% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.800
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intragenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 40% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 49%, "5_TxWk": 27%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, HMG20A, E2F7, SOX2, FOXA1, RXRB, TFAP4, TSC22D4, ATF3, NFIC, ZNF362, RUNX3, PRDM1, CHD7, TP63, KLF5, TEAD1, ELF1, NFE2L2, ZNF217, ESR1, MED26, TP73, USF2, CTCF, JUN, TCF12, EP300, BAF155, GATA6, SOX5, SOX4, RFX5, DEK, E2F1, TEAD4, ZNF92, GTF2F1, TFAP2C, EED, NANOG, CHD8, ZSCAN5D, POU5F1, MYCN, CTBP1, ZBTB48, STAT1, SRF, GATAD1, HIC1, TBP, PAX6, HOXC5, ERG, ETS1, MYC, SMARCA4, RAD21, LHX2, RXRA, NKX2-1, STAT3, UBN1, PRDM14, RCOR1, NR2F6, ARNTL, NR3C1, CEBPB, ESRRA, CREB1, GRHL2, TRPS1, ZHX2, GATA2, FLI1, MRTFB, NCOA2, RUNX1, SMC1A, CEBPA, SIN3A, ZFX, SOX13, AFF4, SMAD3, TWIST1, SMARCC1, CREBBP, ZNF384, RUNX2, CDK6, PBX4, ARNT, DAXX, ATF2, FOXM1, PBX3, MED1, TEAD3, ZEB1, CEBPD, NR1H2, KLF9, MAFK, SP1, NIPBL, USF1, HNF4A, BCL11A, REST, ZBTB7A, ARID1A, ZHX1, ASH2L, SMC3, ELL2, FOXA2, RBBP5, CHD2, MAFF, ZBTB33, HOXB13, BCL3, KDM1A, YY1, RELA, JUNB, BRG1, SP140, HIF1A, OTX2, GATA3, TAL1, MAX, NRIP1, GATA1, CEBPG, NR2F2, TCF7L2, NR2F1, KDM5B, TP53, MYOD1, PHOX2B, BRD2, BHLHE40, AR, PAX3-FOXO1, TAF1, YAP1, EGLN2, EGR1, NOTCH3, BRD4, JUND, MAZ, FOSL2
  • Target gene symbol (double-evidenced CRMs): NRIP1,BTG3
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 0
  • Related genes and loops
  • Related gene: ENSG00000180530, ENSG00000154640,
  • Related loop: chr21:14975000-15000000~~chr21:16550000-16575000, chr21:15000000-15025000~~chr21:16550000-16575000, chr21:16075000-16100000~~chr21:16550000-16575000, chr21:16081685-16083647~~chr21:16561217-16562728, chr21:16175000-16200000~~chr21:16550000-16575000, chr21:16450000-16475000~~chr21:16550000-16575000, chr21:16550000-16575000~~chr21:17450000-17475000, chr21:16550000-16575000~~chr21:17600000-17625000,
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