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Basic information

CohesinDB ID: CDBP00413791

Locus: chr21-16573328-16574192

Data sourse: ENCSR000EFJ, GSE206145, GSE101921, GSE206145-NatGen2015, GSE138105, GSE165895

Cell type: RPE, Fibroblast, SLK, HCAEC, IMR-90, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 5% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 67%, "5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CHD8, PPARG, FOXA2, GTF2B, SMAD3, FOXA1, SRF, HOXB13, ERG, YY1, RELA, RUNX2, ONECUT1, CHD7, RAD21, HIF1A, GATA3, GABPA, TAL1, FOS, MED1, NR3C1, CEBPB, TEAD1, TP53, GRHL2, JUN, TCF12, BRD2, EP300, CTCF, GATA2, EGLN2, FLI1, EED, BRD4, JUND, E2F1, SMC1, TEAD4, AHR, FOSL2

Target gene symbol (double-evidenced CRMs): NRIP1,BTG3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000180530, ENSG00000154640,

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Deatailed information for cohesin site CDBP00413791