- Basic information
- CohesinDB ID: CDBP00413792
- Locus: chr21-16574890-16574992
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 78%,
"5_TxWk": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SFPQ, CSNK2A1, NME2, SP140, DUX4, ZBTB48, E2F1, DDX5, HOXB13
- Target gene symbol (double-evidenced CRMs): BTG3,NRIP1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000180530,
ENSG00000154640,
- Related loop:
chr21:14975000-15000000~~chr21:16550000-16575000,
chr21:15000000-15025000~~chr21:16550000-16575000,
chr21:16050000-16075000~~chr21:16575000-16600000,
chr21:16075000-16100000~~chr21:16550000-16575000,
chr21:16075000-16100000~~chr21:16575000-16600000,
chr21:16175000-16200000~~chr21:16550000-16575000,
chr21:16175000-16200000~~chr21:16575000-16600000,
chr21:16325000-16350000~~chr21:16575000-16600000,
chr21:16400000-16425000~~chr21:16575000-16600000,
chr21:16450000-16475000~~chr21:16550000-16575000,
chr21:16450000-16475000~~chr21:16575000-16600000,
chr21:16453763-16456291~~chr21:16572937-16574492,
chr21:16550000-16575000~~chr21:17450000-17475000,
chr21:16550000-16575000~~chr21:17600000-17625000,
chr21:16575000-16600000~~chr21:16825000-16850000,
chr21:16575000-16600000~~chr21:16850000-16875000,
chr21:16575000-16600000~~chr21:17800000-17825000,