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Basic information

CohesinDB ID: CDBP00413794

Locus: chr21-16579540-16580303

Data sourse: ENCSR230ZWH, GSE126634, GSE206145-NatGen2015, GSE116344, ENCSR917QNE

Cell type: Liver, Fibroblast, RH4, HAP1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Mau2,NIPBL,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 51%, "7_Enh": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, PGR, CHD8, PPARG, FOXA2, BRD3, EZH2phosphoT487, MAFG, SS18, NKX2-2, SOX2, RBPJ, GTF2B, MAFF, CHD2, FOXA1, FOXF1, CDK9, HOXB13, SMARCC1, TWIST1, ERG, TFAP4, RELA, CREBBP, YY1, ASCL1, ONECUT1, RUNX2, NFIC, SMARCA4, CHD7, RAD21, ARNT, HIF1A, PRDM1, GABPA, STAT3, MAFB, CDK8, HAND2, SFPQ, MED1, NR3C1, MAF, TEAD1, CREB1, PIAS1, NEUROG2, NFE2L2, ESR1, PKNOX1, PITX3, C11orf30, GRHL2, MYOD1, BRD2, TCF12, MAFK, SPI1, BAF155, NUP98-HOXA9, HNF4A, AR, GATA2, IRF4, POU2F3, NCOR1, HOXA9, BRD4, BRCA1, PDX1, ZNF316

Target gene symbol (double-evidenced CRMs): C21orf91

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154642,

eachgene

Deatailed information for cohesin site CDBP00413794