Deatailed information for gene ENSG00000154642
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00009783
- Gene Symbol: C21orf91
- Ensembl ID: ENSG00000154642
-
Gene locus: chr21:17788973-17819356
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-16575404-16575871,
chr21-16579540-16580303,
chr21-16583550-16584570,
chr21-16584776-16585081,
chr21-16586117-16589435,
chr21-16592201-16592905,
chr21-16595785-16596040,
chr21-16597851-16598314,
chr21-17352342-17352564,
chr21-17352941-17353720,
chr21-17360708-17361293,
chr21-17364021-17364262,
chr21-17368762-17369199,
chr21-17370093-17370608,
chr21-17371078-17371857,
chr21-17376067-17376842,
chr21-17377529-17377890,
chr21-17383874-17384847,
chr21-17385065-17389738,
chr21-17390128-17390618,
chr21-17391038-17391864,
chr21-17392847-17393210,
chr21-17393972-17394584,
chr21-17427928-17429100,
chr21-17429707-17430271,
chr21-17433211-17433485,
chr21-17434658-17435287,
chr21-17436920-17439074,
chr21-17440398-17441901,
chr21-17442241-17442520,
chr21-17443841-17444029,
chr21-17444297-17444731,
chr21-17447844-17448535,
chr21-17574945-17575093,
chr21-17575466-17576102,
chr21-17579296-17579640,
chr21-17581951-17582360,
chr21-17584154-17587049,
chr21-17592922-17593114,
chr21-17599493-17599842,
chr21-17600958-17601160,
chr21-17602938-17603192,
chr21-17610934-17613664,
chr21-17615995-17616481,
chr21-17650364-17650607,
chr21-17660473-17661158,
chr21-17661485-17661799,
chr21-17662469-17662816,
chr21-17668672-17669176,
chr21-17673220-17674924,
chr21-17676688-17681173,
chr21-17683768-17683914,
chr21-17685520-17685630,
chr21-17688607-17690344,
chr21-17691367-17691688,
chr21-17693819-17694295,
chr21-17694563-17695104,
chr21-17783465-17785440,
chr21-17786174-17786402,
chr21-17786924-17787077,
chr21-17788283-17788550,
chr21-17788766-17789298,
chr21-17789693-17790527,
chr21-17793333-17794084,
chr21-17795350-17796957,
chr21-17797580-17797996,
chr21-17801315-17801609,
chr21-17802147-17803028,
chr21-17804509-17804871,
chr21-17808054-17808570,
chr21-17817153-17820909,
chr21-17900339-17904921,
chr21-17905247-17905528,
chr21-17907747-17907969,
chr21-17911083-17912506,
chr21-17921425-17922537,
chr21-17923497-17927046,
chr21-18109406-18109638,
chr21-18116584-18116748,
chr21-18875172-18876057,
chr21-18877363-18878254,
chr21-18885261-18885334,
-
Co-expression with cohesin genes Rho = 0.5938
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.352
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.891
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: TAMR-MCF7,MB157,hTERT-HME1,H1-Mesenchymal,Olfactory,MCF-7,HEK293T,GM12878,K-562,A-549,HFFc6,HeLa-S3,H9-hESC,HCT-116,H1-hESC,HT-1376,Motor-Neuron,NaiveB,HUES64,SU-DHL-4,RT-112,Skin-Fibroblast,CC-2551,HFF-hTERT,HAP1
- Related loop:
chr21:14075000-14100000~~chr21:17775000-17800000,
chr21:14375000-14400000~~chr21:17775000-17800000,
chr21:15025000-15050000~~chr21:17775000-17800000,
chr21:15725000-15750000~~chr21:17775000-17800000,
chr21:16575000-16600000~~chr21:17800000-17825000,
chr21:17350000-17375000~~chr21:17775000-17800000,
chr21:17375000-17400000~~chr21:17775000-17800000,
chr21:17425000-17450000~~chr21:17775000-17800000,
chr21:17575000-17600000~~chr21:17800000-17825000,
chr21:17600000-17625000~~chr21:17800000-17825000,
chr21:17650000-17675000~~chr21:17775000-17800000,
chr21:17675000-17700000~~chr21:17775000-17800000,
chr21:17675000-17700000~~chr21:17800000-17825000,
chr21:17678482-17679945~~chr21:17817779-17820820,
chr21:17688092-17690151~~chr21:17817660-17820812,
chr21:17775000-17800000~~chr21:17900000-17925000,
chr21:17775000-17800000~~chr21:18100000-18125000,
chr21:17775000-17800000~~chr21:18875000-18900000,
chr21:17775000-17800000~~chr21:23825000-23850000,
chr21:17775000-17800000~~chr21:25175000-25200000,
chr21:17775000-17800000~~chr21:25450000-25475000,
chr21:17775000-17800000~~chr21:25725000-25750000,
chr21:17775000-17800000~~chr21:29000000-29025000,
chr21:17775000-17800000~~chr21:38225000-38250000,
chr21:17800000-17825000~~chr21:17900000-17925000,
chr21:17817784-17820842~~chr21:17901964-17904398,
chr21:17818177-17820852~~chr21:17902238-17904394,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFI8649RQJ, ENCSR662QKG, GSE95015, 4DNFIWZEN3FF, GSE118716, GSE108787, 4DNFI5SUHCGZ, GSE84022, GSE120294, 4DNFIZ4F74QR, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR866FWQ, ENCSR732QOH, 4DNFIYD8LO9Z, GSE155380, GSE97394, GSE80820, 4DNFI9YAVTI1, GSE52457, ENCSR658RQQ, Direct, 4DNFIXWCLD4M, 4DNFIX7H3CE2, 4DNFIV56OFE3, 4DNFI1UEG1HD, ENCSR244BBG, ENCSR393LOP, GSE44267, ENCSR991JXX, 4DNFIOCW5AEM, 4DNFI9ZWZ5BS, 4DNFIFI6NIKJ, ENCSR933UZH, GSE105028, 4DNFIDBIEXI7, 4DNFIZGCA8AH, GSE116869
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: HL-60,SLK,P3HR-1,CMK,HAP1,U2OS,HeLa-S3,Keratinocytes
- Cohesin-DEGs, number of studies: 10
- Cohesin-DEGs, study: GSE83870,GSE140651,GSE131581,GSE154086,GSE138937,GSE126635,GSE89799,GSE130558
- Cohesin-DEGs, subunit: SA2,WAPL,CTCF,SMC1,Rad21