Deatailed information for cohesin site CDBP00413797

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  • Basic information
  • CohesinDB ID: CDBP00413797
  • Locus: chr21-16586117-16589435
  • Data sourse: ENCSR000BLD, ENCSR230ZWH, ENCSR501LQA, GSE126634, GSE116868, ENCSR000BLY, ENCSR404BPV, ENCSR150EFU, GSE25021, ENCSR330ELC, ENCSR000EDW, GSE108869, ENCSR000BUC, ENCSR917QNE, ENCSR000EFJ, GSE165895, GSE86191, GSE138405, GSE101921, GSE152721, GSE206145-NatGen2015, ENCSR198ZYJ, GSE138105, GSE130135, GSE94872, ENCSR895JMI, ENCSR193NSH, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR247LSH, ENCSR000EHX, ENCSR620NWG, ENCSR748MVX, ENCSR767DFK, ENCSR495WGO, ENCSR984DZW, ENCSR217ELF, ENCSR853VWZ, GSE131956, ENCSR676MJK, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE68388, GSE126990, ENCSR000ECS
  • Cell type: SLK, Liver, HuCC-T1, RPE, Fibroblast, HeLa-S3, IMR-90, HFFc6, H1-hESC, MB157, GBM39, SK-N-SH, RT-112, MCF-7, Hela-Kyoto, HCT-116, MCF-10A, HEK293T, Hep-G2, Neurons-H1, A-549, HUVEC, HCAEC, HAP1
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 24% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.733
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: TSS,TES
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 40% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): True
  • Chromatin annotation: "15_Quies": 28%, "2_TssAFlnk": 22%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, NFIA, FOSL1, PGR, ZNF468, HMG20A, ZNF660, SOX2, XBP1, PATZ1, FOXA1, SUZ12, RXRB, SFMBT1, ZFHX2, HNRNPK, ATF3, NFIC, ZNF362, ZBTB44, PRDM1, CHD7, IKZF3, ZNF322, ZNF273, ZNF189, TP63, MITF, CDX2, KLF5, TEAD1, TRIM28, ELF1, ETV1, SNAI2, KLF6, NFE2L2, ZNF217, ESR1, HNF1B, OCA2, PITX3, MED26, USF2, JUN, TCF12, CTCF, BAF155, EP300, POU2F1, MNT, KLF1, SOX5, E2F6, IRF4, RFX5, DEK, E2F1, ZNF528, SMC1, TEAD4, FOXA3, ZNF175, ZNF92, GTF2F1, PDX1, RBPJ, GATAD2A, TFAP2C, GLIS1, NANOG, CHD8, POU2F2, BRD3, POU5F1, MYCN, ZNF263, KDM4C, TOP2A, ZSCAN21, ZBTB17, ZBTB48, ZNF317, SRF, SAP130, HIC1, ARID3A, TBP, ZNF300, ERG, ZNF341, ETS1, ONECUT1, MYC, SMARCA4, KDM4A, HOMEZ, RAD21, TSHZ1, GRHL3, FOXP2, EZH1, RXRA, NKX2-1, GABPA, STAT3, XRCC5, UBN1, NKX3-1, ZNF614, RCOR1, MIER3, ZNF343, ZNF639, ARNTL, NR3C1, CEBPB, ZNF501, CREB1, EZH2, KLF8, GRHL2, FEZF1, EBF3, TRPS1, GABPB1, ZHX2, SPI1, TFE3, EHF, IRF1, ZBTB14, GATA2, ZNF182, ZNF644, FLI1, ZGPAT, MXI1, NFIL3, ZNF76, MRTFB, RUNX1, THAP11, ZNF585A, BCL6, SMC1A, CEBPA, NKX2-2, ZNF335, AFF4, SOX13, SIN3A, POU4F2, SMAD3, ZFP37, NMYC, ERG3, SMARCC1, PRDM10, TWIST1, RARA, ZNF35, ZNF384, CREBBP, RUNX2, CDK6, GATA4, OSR2, ZNF184, NRF1, PBX4, ARNT, BACH1, HMGB2, ATF2, SMAD4, PBX3, MAFB, ZNF10, FOS, CDK8, CHD1, SMARCB1, MED1, CSNK2A1, ZEB1, TEAD3, CEBPD, KDM6B, SCRT2, PIAS1, SUPT16H, ZNF3, NR1H2, KLF9, L3MBTL2, MAFK, SP1, USF1, NIPBL, HNF4A, GSPT2, REST, ARID1A, ZHX1, POU2F3, ASH2L, PHIP, BCOR, FOXP1, GLIS2, AATF, SMC3, ELL2, STAG2, STAG1, CXXC4, ZNF394, SKI, TRP47, PPARG, FOXA2, TBL1X, CHD2, SS18, ZNF600, ZNF692, GTF2B, MAFF, WT1, FOXF1, ZBTB33, TCF7, CDK9, HOXB13, BCL3, KDM1A, YY1, RELA, JUNB, BRG1, ISL1, SP140, HIF1A, PCGF1, OTX2, GATA3, TAL1, MAX, ZNF143, GATA1, HAND2, CEBPG, KLF4, SP7, ZNF223, TCF7L2, NEUROG2, KDM5B, TP53, PKNOX1, NFKB1, ZSCAN22, MYOD1, PHOX2B, ELF3, BRD2, KAT8, ARRB1, NFKBIZ, AR, BHLHE40, TAF1, PAX3-FOXO1, ZNF324, EGLN2, ZNF366, ZBTB42, ZNF280D, ZBTB26, HSF1, NOTCH3, BRD4, JUND, NCOR1, CLOCK, MAZ, BRCA1, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): C21orf91
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 28
  • Related genes and loops
  • Related gene: ENSG00000154642,
  • Related loop: chr21:16050000-16075000~~chr21:16575000-16600000, chr21:16075000-16100000~~chr21:16575000-16600000, chr21:16175000-16200000~~chr21:16575000-16600000, chr21:16325000-16350000~~chr21:16575000-16600000, chr21:16400000-16425000~~chr21:16575000-16600000, chr21:16450000-16475000~~chr21:16575000-16600000, chr21:16575000-16600000~~chr21:16825000-16850000, chr21:16575000-16600000~~chr21:16850000-16875000, chr21:16575000-16600000~~chr21:17800000-17825000, chr21:16586568-16589020~~chr21:17044592-17046378,
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