- Basic information
- CohesinDB ID: CDBP00413795
- Locus: chr21-16583550-16584570
-
Data sourse: GSE98367, GSE138405, ENCSR000BLY, GSE206145-NatGen2015, GSE120943, GSE68388, GSE103477, GSE111537, GSE126990
-
Cell type: Hela-Kyoto, Fibroblast, Monocytes, HuCC-T1, SK-N-SH, OCI-AML-3, THP-1, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: Rad21,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 59%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, CEBPA, ERG, RELA, CTCFL, RAD21, PRDM1, GRHL3, NKX2-1, GABPA, TAL1, MAX, CDK8, MED1, NR3C1, CEBPB, TRIM28, ZNF573, ESR1, TP53, CTCF, BRD2, SPI1, AR, TRIM24, BRD4, SMC3, EED
- Target gene symbol (double-evidenced CRMs): C21orf91
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000154642,
- Related loop:
chr21:16050000-16075000~~chr21:16575000-16600000,
chr21:16075000-16100000~~chr21:16575000-16600000,
chr21:16175000-16200000~~chr21:16575000-16600000,
chr21:16325000-16350000~~chr21:16575000-16600000,
chr21:16400000-16425000~~chr21:16575000-16600000,
chr21:16450000-16475000~~chr21:16575000-16600000,
chr21:16575000-16600000~~chr21:16825000-16850000,
chr21:16575000-16600000~~chr21:16850000-16875000,
chr21:16575000-16600000~~chr21:17800000-17825000,
chr21:16586568-16589020~~chr21:17044592-17046378,