- Basic information
- CohesinDB ID: CDBP00414014
- Locus: chr21-17673220-17674924
-
Data sourse: GSE138405, GSE126990, ENCSR198ZYJ, ENCSR404BPV
-
Cell type: Neurons-H1, Hela-Kyoto
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
60% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 62%,
"7_Enh": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, NANOG, SMARCA2, MYCN, TEAD4, SMAD3, FOXA1, SMARCC1, ZNF384, MYC, CHD7, GRHL3, PBX4, GATA3, STAT3, ETV6, FOS, ARNTL, CEBPB, TEAD1, TP53, ESR1, ZNF334, NFKB1, USF2, JUN, USF1, SP1, TFAP2A, EP300, ZBTB40, GATA2, REST, ASH2L, BRD4, SMC3, TFAP2C
- Target gene symbol (double-evidenced CRMs): CXADR,C21orf91,TMPRSS15
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000154639,
ENSG00000154642,
ENSG00000154646,
- Related loop:
chr21:16375000-16400000~~chr21:17675000-17700000,
chr21:16825000-16850000~~chr21:17650000-17675000,
chr21:17550000-17575000~~chr21:17650000-17675000,
chr21:17650000-17675000~~chr21:17750000-17775000,
chr21:17650000-17675000~~chr21:17775000-17800000,
chr21:17650000-17675000~~chr21:17900000-17925000,
chr21:17650000-17675000~~chr21:18000000-18025000,
chr21:17650000-17675000~~chr21:18050000-18075000,
chr21:17650000-17675000~~chr21:18225000-18250000,
chr21:17650000-17675000~~chr21:18250000-18275000,
chr21:17650000-17675000~~chr21:18375000-18400000,
chr21:17650000-17675000~~chr21:18525000-18550000,
chr21:17675000-17700000~~chr21:17775000-17800000,
chr21:17675000-17700000~~chr21:17800000-17825000,
chr21:17675000-17700000~~chr21:17850000-17875000,
chr21:17675000-17700000~~chr21:17875000-17900000,
chr21:17675000-17700000~~chr21:17900000-17925000,
chr21:17675000-17700000~~chr21:17925000-17950000,
chr21:17675000-17700000~~chr21:17975000-18000000,
chr21:17675000-17700000~~chr21:18025000-18050000,
chr21:17675000-17700000~~chr21:18100000-18125000,
chr21:17675000-17700000~~chr21:18200000-18225000,
chr21:17675000-17700000~~chr21:18225000-18250000,
chr21:17675000-17700000~~chr21:18275000-18300000,
chr21:17675000-17700000~~chr21:18350000-18375000,
chr21:17675000-17700000~~chr21:18600000-18625000,
chr21:17675000-17700000~~chr21:20950000-20975000,
chr21:17675000-17700000~~chr21:27500000-27525000,
chr21:17677615-17680352~~chr21:17901964-17904398,
chr21:17677615-17680352~~chr21:17923881-17926128,
chr21:17677812-17680265~~chr21:17901949-17904160,
chr21:17677812-17680265~~chr21:17924313-17926645,
chr21:17677823-17680312~~chr21:17901986-17904341,
chr21:17677823-17680312~~chr21:17924291-17927223,
chr21:17677849-17680474~~chr21:17901176-17904403,
chr21:17677849-17680474~~chr21:17924257-17926724,
chr21:17677927-17680289~~chr21:17902014-17904745,
chr21:17677927-17680289~~chr21:17924240-17926680,
chr21:17678060-17680287~~chr21:17901956-17904369,
chr21:17678060-17680287~~chr21:17924279-17927173,
chr21:17678109-17680458~~chr21:17901397-17904317,
chr21:17678109-17680458~~chr21:17924273-17926731,
chr21:17678125-17680282~~chr21:17901961-17904290,
chr21:17678127-17680159~~chr21:17902380-17904101,
chr21:17678127-17680159~~chr21:17924472-17926784,
chr21:17678133-17680457~~chr21:17902253-17904403,
chr21:17678134-17680490~~chr21:17901970-17904434,
chr21:17678134-17680490~~chr21:17924283-17926719,
chr21:17678148-17680221~~chr21:17901122-17904107,
chr21:17678148-17680221~~chr21:17924397-17926788,
chr21:17678179-17680164~~chr21:17901225-17904031,
chr21:17678183-17680160~~chr21:17902324-17903958,
chr21:17678183-17680160~~chr21:17924495-17926797,
chr21:17678186-17680190~~chr21:17901236-17904006,
chr21:17678201-17680185~~chr21:17902269-17904057,
chr21:17678201-17680185~~chr21:17924411-17926774,
chr21:17678230-17680476~~chr21:17901968-17904401,
chr21:17678230-17680476~~chr21:17924284-17926668,
chr21:17678232-17680291~~chr21:17902267-17904328,
chr21:17678232-17680291~~chr21:17924273-17926705,
chr21:17678243-17680235~~chr21:17902262-17904303,
chr21:17678243-17680235~~chr21:17924376-17926721,
chr21:17678249-17680466~~chr21:17902018-17904116,
chr21:17678249-17680466~~chr21:17924313-17926669,
chr21:17678253-17680475~~chr21:17902276-17904784,
chr21:17678253-17680475~~chr21:17924113-17926084,
chr21:17678257-17680250~~chr21:17901952-17904689,
chr21:17678257-17680250~~chr21:17924370-17926081,
chr21:17678261-17680309~~chr21:17902245-17904789,
chr21:17678261-17680309~~chr21:17924244-17926698,
chr21:17678268-17680024~~chr21:17901970-17904396,
chr21:17678268-17680024~~chr21:17924382-17926045,
chr21:17678273-17680232~~chr21:17901976-17904341,
chr21:17678273-17680232~~chr21:17924311-17926659,
chr21:17678274-17680496~~chr21:17901990-17904210,
chr21:17678274-17680496~~chr21:17924317-17926677,
chr21:17678275-17679993~~chr21:17902250-17904345,
chr21:17678275-17679993~~chr21:17924375-17926695,
chr21:17678276-17680252~~chr21:17902239-17904213,
chr21:17678276-17680252~~chr21:17924115-17926703,
chr21:17678279-17680475~~chr21:17902065-17904288,
chr21:17678299-17680259~~chr21:17924330-17926663,
chr21:17678306-17680047~~chr21:17901389-17904158,
chr21:17678306-17680047~~chr21:17924232-17925966,
chr21:17678316-17680058~~chr21:17902232-17904144,
chr21:17678316-17680058~~chr21:17924329-17925933,
chr21:17678318-17680109~~chr21:17924273-17926069,
chr21:17678321-17680260~~chr21:17902253-17904292,
chr21:17678321-17680260~~chr21:17924254-17926747,
chr21:17678321-17680290~~chr21:17901939-17904304,
chr21:17678321-17680290~~chr21:17924188-17926114,
chr21:17678335-17680284~~chr21:17902210-17904283,
chr21:17678360-17680330~~chr21:17902269-17904310,
chr21:17678360-17680330~~chr21:17924174-17926108,
chr21:17678382-17680217~~chr21:17902287-17903894,
chr21:17678406-17680047~~chr21:17924235-17926067,
chr21:17678407-17680331~~chr21:17902187-17904333,
chr21:17678407-17680331~~chr21:17924341-17926046,
chr21:17678440-17680173~~chr21:17902403-17904032,
chr21:17678440-17680173~~chr21:17924485-17926802,
chr21:17678442-17679985~~chr21:17924612-17926635,
chr21:17678447-17680004~~chr21:17924354-17926683,
chr21:17678473-17680046~~chr21:17902405-17904120,
chr21:17678473-17680046~~chr21:17924396-17926719,
chr21:17678473-17680046~~chr21:18368458-18370081,
chr21:17678482-17679945~~chr21:17817779-17820820,
chr21:17678482-17679945~~chr21:17901964-17904175,
chr21:17678505-17680271~~chr21:17901920-17904293,
chr21:17678516-17679996~~chr21:17924566-17926674,