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Basic information

CohesinDB ID: CDBP00414045

Locus: chr21-17788766-17789298

Data sourse: GSE206145, GSE120943

Cell type: Monocytes, B-cell

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Rad21,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TSS,TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 65%, "7_Enh": 13%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: CBX5, SOX2, NME2, FOXA1, LYL1, NFIC, RUNX3, CBFB, MAF, JMJD1C, BCLAF1, ZNF217, LMO2, BAF155, MNT, DPF2, RAD51, TEAD4, RUNX1T1, TOP2A, MTA2, ZBTB48, NBN, ARID3A, ERG, NFKB2, MYC, RAD21, GABPA, NKX3-1, IKZF1, CEBPB, STAT5B, KMT2A, CREB1, SPI1, IRF1, GATA2, RELB, RUNX1, SMC1A, BCL6, CEBPA, TRIM22, MEF2A, NOTCH1, ATF2, ETV6, FOXM1, SUPT5H, CDK8, MED1, PML, MYB, PIAS1, SMAD1, STAT5A, NIPBL, BCL11A, SP1, ATF7, POU2F3, ASH2L, TCF3, FOXP1, MLLT1, NFATC3, SKI, MEF2B, MTA3, CREM, EBF1, NFATC1, E2F8, MEF2C, TCF7, CDK9, RELA, TARDBP, JUNB, GATA3, BATF, TAL1, GATA1, AGO2, TCF7L2, TP53, NFKB1, PHOX2B, TBX21, AR, ZBTB40, IKZF2, BRD4, ZNF24

Target gene symbol (double-evidenced CRMs): C21orf91,USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 15

Number of somatic mutations (non-coding): 15

Related genes and loops

Related gene: ENSG00000155313, ENSG00000154642,

eachgene

Deatailed information for cohesin site CDBP00414045