- Basic information
- CohesinDB ID: CDBP00413929
- Locus: chr21-17393972-17394584
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Data sourse: GSE206145-GSE177045, GSE67783
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Cell type: MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 84%,
"5_TxWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CHD8, FOXA2, LDB1, EBF1, SOX2, ZFX, POU4F2, HNF1A, DUX4, FOXA1, ERG, KDM1A, RELA, CREBBP, ASCL1, MYC, SMARCA4, CHD7, HIF1A, NKX2-1, ATF2, GATA3, TAL1, MAX, NKX3-1, GATA1, TLE3, NR3C1, TEAD3, TEAD1, TRIM28, TCF7L2, PIAS1, ESR1, GRHL2, BCL11A, BAF155, SPI1, AR, GATA2, POU2F3, JUND, TFAP2C, EED
- Target gene symbol (double-evidenced CRMs): BTG3,C21orf91,CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000154639,
ENSG00000154640,
ENSG00000154642,
- Related loop:
chr21:16925000-16950000~~chr21:17375000-17400000,
chr21:17375000-17400000~~chr21:17500000-17525000,
chr21:17375000-17400000~~chr21:17550000-17575000,
chr21:17375000-17400000~~chr21:17575000-17600000,
chr21:17375000-17400000~~chr21:17775000-17800000,
chr21:17375000-17400000~~chr21:17825000-17850000,
chr21:17386038-17389021~~chr21:17553442-17555850,
chr21:17386038-17389021~~chr21:17584614-17587020,
chr21:17386054-17389016~~chr21:17553561-17555841,
chr21:17386054-17389016~~chr21:17584615-17586797,
chr21:17386098-17389064~~chr21:17553871-17555565,
chr21:17386098-17389064~~chr21:17584658-17586849,
chr21:17386110-17389253~~chr21:17583722-17586723,
chr21:17386118-17388987~~chr21:17553707-17555628,
chr21:17386118-17388987~~chr21:17584710-17586759,