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Basic information

CohesinDB ID: CDBP00414052

Locus: chr21-17804509-17804871

Data sourse: ENCSR000BTQ, GSE72082, GSE138405, ENCSR000BLY, GSE105028, GSE206145, ENCSR703TNG, GSE25021, GSE50893

Cell type: MCF-7, RPE, Hela-Kyoto, GM2610, SK-N-SH, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 68%, "4_Tx": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXA2, NKX2-2, GTF2B, DUX4, STAT1, FOXA1, HOXB13, ZBTB2, NEUROD1, MYC, EZH1, GATA4, RAD21, ZNF429, OTX2, GATA3, GABPA, MAFB, NKX3-1, ZNF143, SUPT5H, MITF, ARNTL, SCRT2, EZH2, STAG1, USF2, CTCF, USF1, SPI1, INTS13, FLI1, BRD4, SCRT1, PDX1

Target gene symbol (double-evidenced CRMs): BTG3,CXADR,C21orf91

Function elements

Human SNPs: .

Number of somatic mutations (coding): 3

Number of somatic mutations (non-coding): 1

Related genes and loops

Related gene: ENSG00000154639, ENSG00000154640, ENSG00000154642,

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Deatailed information for cohesin site CDBP00414052