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Basic information

CohesinDB ID: CDBP00414048

Locus: chr21-17795350-17796957

Data sourse: ENCSR167MTG, ENCSR230ZWH, GSE72082, GSE138405, ENCSR054FKH, ENCSR000EDE, GSE126990, GSE50893, ENCSR000EDW, ENCSR917QNE

Cell type: Hela-Kyoto, SNYDER, Hep-G2, HeLa-S3, Liver

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SMC3,Rad21,SA2,SA1

CTCF binding site: CTCF CTCF motif: False

Genomic location: TSS

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 45%, "4_Tx": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: MED1, RELA, ZNF384, CEBPB, CHD8, CEBPA, TRIM28, MYB, KMT2A, AFF4, CREB1, CREM, RUNX3, MYC, BRD4, FOXA1, RELB, SPI1, ERG

Target gene symbol (double-evidenced CRMs): C21orf91,USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 114

Number of somatic mutations (non-coding): 38

Related genes and loops

Related gene: ENSG00000155313, ENSG00000154642,

eachgene

Deatailed information for cohesin site CDBP00414048