- Basic information
- CohesinDB ID: CDBP00413936
- Locus: chr21-17427928-17429100
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Data sourse: GSE93080, GSE206145, GSE206145-NatGen2015, GSE62063, GSE50893
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Cell type: GM2630, Fibroblast, GM18505, GM2610, GM19240, GM12878, Ramos, GM18486, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.900
- Subunit: NIPBL,SA1,SMC1,SA2,Mau2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 83%,
"5_TxWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF394, RUNX1, ZNF426, MEF2B, SMC1A, ZNF697, CBX5, EBF1, ZFX, MTA2, FOXA1, ERG, MEF2A, RELA, CHD4, TARDBP, ZNF384, PAX6, JUNB, PBX1, MYC, NFIC, ZFP64, SMARCA4, RUNX3, SP140, SKIL, HIF1A, PRDM12, ZNF781, ATF2, ZNF518A, BATF, PAX5, SOX10, FOXM1, FOS, IKZF1, BACH2, BCLAF1, KMT2A, ZBTB11, TFAP2C, NR2F1, EZH2, ESR1, YY1, ZHX2, TCF12, NIPBL, BCL11A, TBX21, AR, TAF1, PAX8, DPF2, ARID1A, HDGF, IRF4, IKZF2, BRD4, TCF3, BCOR, RELB, ZNF623, ZC3H11A, ZNF34, MLLT1, RBPJ, EED
- Target gene symbol (double-evidenced CRMs): CXADR,C21orf91
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops