- Basic information
- CohesinDB ID: CDBP00413996
- Locus: chr21-17574945-17575093
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Data sourse: GSE120943, GSE98367
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Cell type: Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
60% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 57%,
"5_TxWk": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU5F1, RBM22, ARNT, ZSCAN16, PHIP, SPI1, ATF2, PRDM9, FOXA1, ZNF614, SPIB, GATA1, AGO2
- Target gene symbol (double-evidenced CRMs): C21orf91,USP25,CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 4
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000155313,
ENSG00000154639,
ENSG00000154642,
- Related loop:
chr21:15875000-15900000~~chr21:17575000-17600000,
chr21:16925000-16950000~~chr21:17550000-17575000,
chr21:16925000-16950000~~chr21:17575000-17600000,
chr21:17050000-17075000~~chr21:17550000-17575000,
chr21:17100000-17125000~~chr21:17550000-17575000,
chr21:17375000-17400000~~chr21:17550000-17575000,
chr21:17375000-17400000~~chr21:17575000-17600000,
chr21:17400000-17425000~~chr21:17550000-17575000,
chr21:17400000-17425000~~chr21:17575000-17600000,
chr21:17425000-17450000~~chr21:17550000-17575000,
chr21:17550000-17575000~~chr21:17650000-17675000,
chr21:17575000-17600000~~chr21:17800000-17825000,