- Basic information
- CohesinDB ID: CDBP00413927
- Locus: chr21-17391038-17391864
-
Data sourse: GSE98367, GSE206145, GSE206145-NatGen2015, GSE120943, GSE68388
-
Cell type: RPE, Fibroblast, Monocytes, HuCC-T1, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 89%,
"14_ReprPCWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, FOXA2, CEBPA, GTF2B, SMAD3, FOXA1, HOXB13, ERG, RELA, ASCL1, JUNB, GATA4, GRHL3, HIF1A, PBX4, ARNT, NKX2-1, STAT3, TP63, ZSCAN4, FOS, ESRRA, TCF7L2, CCAR2, ESR1, GRHL2, NFKB1, JUN, BAF155, AR, GATA2, JUND, FOXP1, PDX1
- Target gene symbol (double-evidenced CRMs): C21orf91,BTG3,CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000154639,
ENSG00000154640,
ENSG00000154642,
- Related loop:
chr21:16925000-16950000~~chr21:17375000-17400000,
chr21:17375000-17400000~~chr21:17500000-17525000,
chr21:17375000-17400000~~chr21:17550000-17575000,
chr21:17375000-17400000~~chr21:17575000-17600000,
chr21:17375000-17400000~~chr21:17775000-17800000,
chr21:17375000-17400000~~chr21:17825000-17850000,
chr21:17385933-17388190~~chr21:17554000-17555508,
chr21:17385933-17388190~~chr21:17585378-17586847,
chr21:17385938-17388768~~chr21:17553974-17555843,
chr21:17385938-17388768~~chr21:17584830-17586831,
chr21:17385938-17388768~~chr21:17924257-17926724,
chr21:17385982-17388062~~chr21:17584894-17587061,
chr21:17385997-17387993~~chr21:17511653-17514907,
chr21:17385997-17387993~~chr21:17553561-17555852,
chr21:17385997-17387993~~chr21:17584718-17586899,
chr21:17386011-17388740~~chr21:17553679-17555816,
chr21:17386026-17387946~~chr21:17553932-17555551,
chr21:17386031-17388049~~chr21:17584682-17586783,
chr21:17386036-17388915~~chr21:17511577-17514929,
chr21:17386036-17388915~~chr21:17553843-17555843,
chr21:17386036-17388915~~chr21:17584766-17586992,
chr21:17386038-17389021~~chr21:17553442-17555850,
chr21:17386038-17389021~~chr21:17584614-17587020,
chr21:17386049-17388075~~chr21:17585127-17586877,
chr21:17386054-17389016~~chr21:17553561-17555841,
chr21:17386054-17389016~~chr21:17584615-17586797,
chr21:17386056-17387970~~chr21:17585070-17586716,
chr21:17386064-17388904~~chr21:17584829-17586982,
chr21:17386066-17388182~~chr21:17584650-17586844,
chr21:17386069-17388018~~chr21:17553849-17555556,
chr21:17386069-17388018~~chr21:17584882-17586850,
chr21:17386074-17388534~~chr21:17511356-17514781,
chr21:17386074-17388534~~chr21:17553871-17555826,
chr21:17386074-17388534~~chr21:17584717-17586949,
chr21:17386077-17388636~~chr21:17511764-17514939,
chr21:17386077-17388636~~chr21:17553840-17555851,
chr21:17386077-17388636~~chr21:17584710-17587013,
chr21:17386079-17388476~~chr21:17584668-17586918,
chr21:17386098-17389064~~chr21:17553871-17555565,
chr21:17386098-17389064~~chr21:17584658-17586849,
chr21:17386110-17389253~~chr21:17583722-17586723,
chr21:17386111-17388007~~chr21:17553874-17555626,
chr21:17386111-17388007~~chr21:17585385-17586756,
chr21:17386112-17388058~~chr21:17585381-17586741,
chr21:17386118-17388987~~chr21:17553707-17555628,
chr21:17386118-17388987~~chr21:17584710-17586759,
chr21:17386120-17388090~~chr21:17584777-17586913,
chr21:17386123-17388073~~chr21:17554074-17555851,
chr21:17386142-17388075~~chr21:17584963-17586801,
chr21:17386143-17388031~~chr21:17553907-17555596,
chr21:17386155-17388075~~chr21:17584973-17586950,
chr21:17386210-17388145~~chr21:17585190-17586791,
chr21:17386226-17388006~~chr21:17585307-17586805,
chr21:17386232-17388143~~chr21:17585338-17586757,
chr21:17386274-17388142~~chr21:17585346-17586763,
chr21:17386451-17388123~~chr21:17585377-17586812,
chr21:17386457-17388148~~chr21:17585337-17586760,
chr21:17386482-17388045~~chr21:17585364-17586763,
chr21:17386482-17388045~~chr21:17924411-17926774,
chr21:17386521-17388914~~chr21:17584891-17586781,
chr21:17386573-17387885~~chr21:17585423-17586769,
chr21:17386602-17387861~~chr21:17585457-17586613,