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Basic information

CohesinDB ID: CDBP00414019

Locus: chr21-17691367-17691688

Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191

Cell type: Fibroblast, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 60% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 80%, "5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, FOXA1, RBFOX2, PBX2, ZFHX2, NFIC, CHD7, PRDM1, TP63, TEAD1, E2F5, ETV1, NFE2L2, ESR1, HDAC8, CTCF, JUN, BAF155, PYGO2, CREB3, DDX20, ZNF175, TFAP2C, MYCN, ID3, ZBTB48, HINFP, SRF, MLLT3, NBN, SP4, HOXC5, ERG, OGG1, MYC, RFX1, ARID1B, RAD21, STAT3, ZNF398, IKZF1, NFE2, ZNF639, NR3C1, IRF1, ZNF644, ATF1, GTF2A2, SMC1A, SIN3A, ZFX, ZNF335, SMAD3, ZBTB2, ZNF384, NRF1, PBX4, BACH1, NR2C1, FOS, ZNF584, C11orf30, L3MBTL2, SETDB1, NR4A1, SMC3, ILK, STAG2, PTTG1, TRP47, FOXA2, WT1, ZNF574, ZBTB33, HOXB13, ZNF589, YY1, RELA, ZNF148, NEUROD1, CHAMP1, SP140, OTX2, GATA3, MAX, ZNF740, HAND2, ZNF592, ZKSCAN8, TCF7L2, BRD2, BHLHE40, PTRF, BRD4, JUND, MAZ, IRF9, TBX2, MEF2D, ZNF24, AHR

Target gene symbol (double-evidenced CRMs): TMPRSS15,C21orf91

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000154642, ENSG00000154646,

eachgene

Deatailed information for cohesin site CDBP00414019