- Basic information
- CohesinDB ID: CDBP00414068
- Locus: chr21-17911083-17912506
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Data sourse: GSE206145-NatGen2015, GSE67783, GSE86191
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Cell type: Fibroblast, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
47% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 81%,
"14_ReprPCWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: GTF2B, SMAD3, MAFF, HOXB13, KDM1A, JUNB, GRHL3, PBX4, DAXX, NKX2-1, GABPA, FOS, NR3C1, ZEB1, TRIM28, EZH2, ESR1, NFKB1, JUN, MAFK, BCL11A, BRD4, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): C21orf91,BTG3
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 6
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000154640,
ENSG00000154642,
- Related loop:
chr21:17350000-17375000~~chr21:17900000-17925000,
chr21:17600000-17625000~~chr21:17900000-17925000,
chr21:17650000-17675000~~chr21:17900000-17925000,
chr21:17675000-17700000~~chr21:17900000-17925000,
chr21:17700000-17725000~~chr21:17900000-17925000,
chr21:17725000-17750000~~chr21:17900000-17925000,
chr21:17750000-17775000~~chr21:17900000-17925000,
chr21:17775000-17800000~~chr21:17900000-17925000,
chr21:17800000-17825000~~chr21:17900000-17925000,