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Basic information

CohesinDB ID: CDBP00414051

Locus: chr21-17802147-17803028

Data sourse: GSE206145-NatGen2015, ENCSR153HNT, GSE138105

Cell type: K-562, SLK, Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 47% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 60%, "4_Tx": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXA2, ZFX, ZNF317, DUX4, ZSCAN5A, SMAD3, FOXA1, WT1, ERG, TFAP4, JUNB, MYC, RUNX2, PBX4, GRHL3, ARNT, GATA3, PBX3, ZNF143, SUPT5H, CDK8, FOS, CEBPB, SNAI2, MYOD1, JUN, ZHX2, TCF12, SPI1, TBX21, BHLHE40, AR, FLI1, NOTCH3, JUND, BRD4, MAZ, MRTFB, TEAD4, PDX1, FOSL2

Target gene symbol (double-evidenced CRMs): C21orf91,CXADR,BTG3

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154639, ENSG00000154640, ENSG00000154642,

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Deatailed information for cohesin site CDBP00414051