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Basic information

CohesinDB ID: CDBP00414020

Locus: chr21-17693819-17694295

Data sourse: GSE86191, GSE67783, GSE68388

Cell type: HCT-116, HSPC, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 60% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 80%, "7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, FOXO1, TRP47, CBX1, RUNX1T1, ZFX, DUX4, MAFF, ZBTB48, STAT1, ZNF300, RELA, ZNF90, GRHL3, BATF3, GABPA, HMBOX1, MAX, CEBPB, DIDO1, ELF1, MYB, ETV1, C11orf30, CTCF, MAFK, SPI1, BCL11A, TBX21, LMO1, GATA2, IRF4, NOTCH3, MAZ, ZNF316

Target gene symbol (double-evidenced CRMs): C21orf91,TMPRSS15

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000154642, ENSG00000154646,

eachgene

Deatailed information for cohesin site CDBP00414020