- Basic information
- CohesinDB ID: CDBP00413998
- Locus: chr21-17579296-17579640
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Data sourse: GSE206145-NatGen2015
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Cell type: Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: SA1,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
60% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 65%,
"5_TxWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF426, ZSCAN5C, MEIS2, FOXA1, PBX2, HNRNPK, ZNF362, ZBTB44, PRDM1, KLF10, ESR1, BAF155, EP300, KLF3, TEAD4, TFAP2C, NANOG, CHD8, TOP2A, ERF, DUX4, ZBTB48, ZNF205, SRF, HIC1, ERG, MYC, GABPA, NKX3-1, VDR, ZNF750, CEBPB, CREB1, FEZF1, EBF3, GATA2, ZIM3, RUNX1, CEBPA, ZFX, ZFP37, SMARCC1, ZNF384, ZNF35, RUNX2, OSR2, ARNT, PBX4, SOX11, ATF2, ZNF10, SCRT2, PIAS1, ZNF22, RBM22, BCL11A, ARID1A, ASH2L, PHIP, FOXP1, PRDM6, ZNF34, ZNF394, PPARG, FOXA2, ZSCAN16, GTF2B, WT1, HOXB13, KDM1A, RELA, BRG1, ISL1, OTX2, AGO2, TLE3, BCL11B, SP7, PKNOX1, ZNF843, AR, ZNF366, ZBTB42, ZBTB26, BRD4, SCRT1, CLOCK
- Target gene symbol (double-evidenced CRMs): C21orf91,USP25,CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000155313,
ENSG00000154639,
ENSG00000154642,
- Related loop:
chr21:15875000-15900000~~chr21:17575000-17600000,
chr21:16925000-16950000~~chr21:17550000-17575000,
chr21:16925000-16950000~~chr21:17575000-17600000,
chr21:17050000-17075000~~chr21:17550000-17575000,
chr21:17100000-17125000~~chr21:17550000-17575000,
chr21:17375000-17400000~~chr21:17550000-17575000,
chr21:17375000-17400000~~chr21:17575000-17600000,
chr21:17386038-17389021~~chr21:17584614-17587020,
chr21:17386054-17389016~~chr21:17584615-17586797,
chr21:17386110-17389253~~chr21:17583722-17586723,
chr21:17400000-17425000~~chr21:17550000-17575000,
chr21:17400000-17425000~~chr21:17575000-17600000,
chr21:17425000-17450000~~chr21:17550000-17575000,
chr21:17550000-17575000~~chr21:17650000-17675000,
chr21:17575000-17600000~~chr21:17800000-17825000,