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Basic information

CohesinDB ID: CDBP00414003

Locus: chr21-17600958-17601160

Data sourse: GSE206145-NatGen2015

Cell type: Fibroblast

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: SA1,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 60% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 54%, "5_TxWk": 45%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, ZNF660, SOX2, NME2, FOXA1, RBFOX2, LEO1, ATF3, NFIC, ZNF362, ZBTB44, RUNX3, IKZF3, PRDM1, ZNF532, GLYR1, ZNF189, TP63, MAF, ZNF629, TEAD1, ZNF121, SMAD5, ESR1, JUN, TCF12, CTCF, BAF155, GATA6, PAX8, PRDM4, IRF4, E2F4, GATAD2A, EED, POU5F1, TOP2A, ZNF317, ZSCAN21, DUX4, ZBTB48, ZNF134, GATAD1, DDX5, HIC1, ERG, USP7, OGG1, MYC, GRHL3, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, IKZF1, ZNF639, NR3C1, CEBPB, KMT2A, CREB1, FEZF1, ZNF652, EBF3, SPI1, ZNF664, IRF1, GATA2, ZNF766, ZIM3, RUNX1, CEBPA, POU4F2, SMAD3, ZFP37, SMARCC1, PRDM10, MEF2A, ZNF384, ZNF35, RUNX2, GATA4, OSR2, ZNF184, ARNT, PBX4, DAXX, ATF2, PRDM9, HMBOX1, PBX3, MAFB, ZNF10, SUPT5H, CDK8, FOS, MED1, PML, TERF1, PIAS1, ZNF879, NUP98-HOXA9, RBM22, SP1, BCL11A, USF1, HNF4A, ZNF479, HOXA9, PHIP, FOXP1, PRDM6, ZNF34, ZNF394, PPARG, FOXA2, CREM, PAF1, NFATC1, ZSCAN16, GTF2B, ZBED1, WT1, ZNF823, HOXB13, BCL3, MPHOSPH8, KDM1A, RELA, NEUROD1, JUNB, BRG1, HIF1A, GATA3, BATF, SPIB, GATA1, AGO2, TLE3, CEBPG, SP7, PKNOX1, ZNF334, NFKB1, PHOX2B, T, TBX21, AR, ZNF324, ZBTB42, ZNF366, MYNN, IKZF2, BRD4, ILF3, JUND, CLOCK, ZNF440, ZSCAN23, ZZZ3, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): BTG3,C21orf91,USP25

Function elements

Human SNPs: .

Number of somatic mutations (coding): 6

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000155313, ENSG00000154640, ENSG00000154642,

eachgene

Deatailed information for cohesin site CDBP00414003