- Basic information
- CohesinDB ID: CDBP00414001
- Locus: chr21-17592922-17593114
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Data sourse: GSE62063
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Cell type: Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: NIPBL
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
60% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 66%,
"4_Tx": 28%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, ZNF660, SOX2, NME2, FOXA1, RBFOX2, LEO1, ATF3, NFIC, ZNF362, ZBTB44, RUNX3, IKZF3, PRDM1, ZNF532, GLYR1, ZNF189, TP63, MAF, ZNF629, TEAD1, ZNF121, SMAD5, ESR1, JUN, TCF12, CTCF, BAF155, GATA6, PAX8, PRDM4, IRF4, E2F4, GATAD2A, EED, POU5F1, TOP2A, ZNF317, ZSCAN21, DUX4, ZBTB48, ZNF134, GATAD1, DDX5, HIC1, ERG, USP7, OGG1, MYC, GRHL3, RXRA, NKX2-1, GABPA, STAT3, NKX3-1, IKZF1, ZNF639, NR3C1, CEBPB, KMT2A, CREB1, FEZF1, ZNF652, EBF3, SPI1, ZNF664, IRF1, GATA2, ZNF766, ZIM3, RUNX1, CEBPA, POU4F2, SMAD3, ZFP37, SMARCC1, PRDM10, MEF2A, ZNF384, ZNF35, RUNX2, GATA4, OSR2, ZNF184, ARNT, PBX4, DAXX, ATF2, PRDM9, HMBOX1, PBX3, MAFB, ZNF10, SUPT5H, CDK8, FOS, MED1, PML, TERF1, PIAS1, ZNF879, NUP98-HOXA9, RBM22, SP1, BCL11A, USF1, HNF4A, ZNF479, HOXA9, PHIP, FOXP1, PRDM6, ZNF34, ZNF394, PPARG, FOXA2, CREM, PAF1, NFATC1, ZSCAN16, GTF2B, ZBED1, WT1, ZNF823, HOXB13, BCL3, MPHOSPH8, KDM1A, RELA, NEUROD1, JUNB, BRG1, HIF1A, GATA3, BATF, SPIB, GATA1, AGO2, TLE3, CEBPG, SP7, PKNOX1, ZNF334, NFKB1, PHOX2B, T, TBX21, AR, ZNF324, ZBTB42, ZNF366, MYNN, IKZF2, BRD4, ILF3, JUND, CLOCK, ZNF440, ZSCAN23, ZZZ3, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): USP25,BTG3,C21orf91,CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000155313,
ENSG00000154639,
ENSG00000154640,
ENSG00000154642,
- Related loop:
chr21:15875000-15900000~~chr21:17575000-17600000,
chr21:16925000-16950000~~chr21:17575000-17600000,
chr21:17375000-17400000~~chr21:17575000-17600000,
chr21:17400000-17425000~~chr21:17575000-17600000,
chr21:17575000-17600000~~chr21:17800000-17825000,
chr21:17597892-17599183~~chr21:17611016-17612344,