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Basic information

CohesinDB ID: CDBP00413873

Locus: chr21-17051166-17051326

Data sourse: GSE105028, GSE206145-NatGen2015

Cell type: Fibroblast, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: Mau2,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 31% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 66%, "7_Enh": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, NANOG, PGR, CHD8, FOXA2, POU5F1, MYCN, TOP2A, SOX2, CHD2, DUX4, FOXF1, FOXA1, CDK9, HOXB13, TWIST1, SMARCC1, KDM1A, ERG, RELA, CREBBP, ONECUT1, SMARCA4, CHD7, RAD21, ISL1, ARNT, SOX11, HIF1A, GATA3, GABPA, NRIP1, FOS, RCOR1, HAND2, NR3C1, KLF4, ZNF750, NCOA3, TEAD1, ZEB1, ZNF26, TP53, ESR1, PITX3, ZNF334, EBF3, PHOX2B, BRD2, T, NUP98-HOXA9, BCL11A, EP300, SP1, TFAP2A, AR, GATA6, HDAC2, GATA2, EGLN2, FLI1, TEAD4, TBX2, TFAP2C, FOSL2

Target gene symbol (double-evidenced CRMs): USP25,CXADR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000155313, ENSG00000154639,

eachgene

Deatailed information for cohesin site CDBP00413873