- Basic information
- CohesinDB ID: CDBP00413881
- Locus: chr21-17105633-17106526
-
Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE72082, GSE138405, GSE25021, GSE76893, ENCSR000EDE, ENCSR703TNG, GSE126990, GSE108869, ENCSR000ECS
-
Cell type: MCF-7, HeLa-S3, Hela-Kyoto
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 6% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
31% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 81%,
"9_Het": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, FOXA1, ZNF444, SMARCE1, TEAD1, ELF1, COBLL1, ESR1, ZNF217, CTCF, TCF12, JUN, BAF155, EP300, DPF2, TEAD4, TFAP2C, NANOG, ZNF263, KDM4C, CTBP1, ZSCAN5A, ERG, USP7, EZH1, MYC, RAD21, GABPA, STAT3, NKX3-1, RCOR1, DNMT3B, ZNF750, CEBPB, NR3C1, CREB1, GRHL2, TRPS1, GATA2, GATAD2B, SMC1A, SIN3A, ZFX, ZXDC, CREBBP, GR, ARNT, NFIB, PBX4, FOS, MED1, SCRT2, PIAS1, SETDB1, ATF7, ASH2L, CTBP2, MBD2, FOXP1, HOXB13, RELA, TARDBP, NEUROD1, HIF1A, GATA3, MAX, GATA1, ZNF143, CBX2, TLE3, NCOA3, NR2F2, KDM5B, PKNOX1, AR, ZNF579, EGLN2, NCOR1, NOTCH3, BRD4, JUND, CUX1, MAZ, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 5
- Related genes and loops