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Basic information

CohesinDB ID: CDBP00413883

Locus: chr21-17119410-17120229

Data sourse: GSE105028, GSE97394, ENCSR198ZYJ, ENCSR404BPV

Cell type: Neurons-H1, HUES64, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 31% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 82%, "7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PGR, CHD8, PPARG, NANOG, ZNF263, POU5F1, TOP2A, SOX2, ZNF534, TEAD4, SMAD3, FOXA1, HNF4G, ERG, KDM1A, RELA, CREBBP, YY1, RUNX2, GR, RAD21, CHD7, ARNT, HIF1A, GATA3, PRDM9, GABPA, TAL1, PAX5, MAX, NRIP1, NKX3-1, ARNTL, NR3C1, NCOA3, TEAD1, NR2F2, TRIM28, TCF7L2, PIAS1, EZH2, SMAD1, ESR1, GRHL2, SETDB1, CTCF, BAF155, SP1, EP300, BCL11A, AR, HDAC2, GATA2, REST, ASH2L, BRD4, CLOCK, NCOA2, AHR

Target gene symbol (double-evidenced CRMs): CXADR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000154639,

eachgene

Deatailed information for cohesin site CDBP00413883