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Basic information

CohesinDB ID: CDBP00413884

Locus: chr21-17120454-17120726

Data sourse: GSE76893, GSE72082

Cell type: MCF-7

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: NIPBL,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 31% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 86%, "9_Het": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, CTBP1, FOXA1, HOXB13, RELA, ZXDC, CREBBP, HIF1A, GATA3, NRIP1, MED1, NCOA3, ZNF217, ESR1, NIPBL, EP300, AR, GATAD2B, CTBP2, MBD2, NCOA2, AHR

Target gene symbol (double-evidenced CRMs): CXADR

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000154639,

eachgene

Deatailed information for cohesin site CDBP00413884