- Basic information
- CohesinDB ID: CDBP00413975
- Locus: chr21-17515319-17515802
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Data sourse: ENCSR000BLD, GSE206145-NatGen2015, GSE67783
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Cell type: H1-hESC, Fibroblast, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
60% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"14_ReprPCWk": 23%,
"5_TxWk": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NFIA, TRIM25, ZNF675, NME2, FOXA1, HLF, RXRB, MLL4, KDM3A, THAP1, ZBTB44, IKZF3, MORC2, PAX5, SFPQ, TEAD1, ZNF121, LMO2, OCA2, MED26, PITX3, ZNF561, E4F1, ARID5B, SOX5, E2F4, DEK, RFX3, KLF3, KMT2B, GATAD2A, JARID2, NANOG, ZNF263, BRD3, POU5F1, TOP2A, CTBP1, ERF, STAT1, ZNF134, SAP130, ERG, ZBTB21, ZBTB8A, EZH1, SMARCA4, RFX1, UBN1, ZNF398, RCOR1, NR2F6, CEBPB, HNRNPL, CREB1, GABPB1, ZHX2, MIXL1, KLF17, ZNF257, GATA2, ZNF644, MXD3, FLI1, DRAP1, MXI1, HCFC1, RUVBL2, RUNX1, CEBPA, NKX2-2, HDAC1, TBX3, SP5, SMARCC1, PRDM10, ZBTB2, TFDP1, ZBTB10, ELK1, ATF2, FOXM1, SP2, SMARCB1, PIAS1, NR1H2, C11orf30, MBD1, IKZF5, ARID2, ELL2, ETV4, NFATC3, CREM, CHD2, PAF1, SS18, ZNF460, ZSCAN16, NFATC1, WT1, MEF2C, NEUROD1, JUNB, MAF1, PLAG1, KLF4, BCL11B, ZFP69B, ZBTB6, EGR2, ELF3, ARID4B, RXR, EGLN2, ZNF366, HSF1, ZBTB26, NCOR1, ILF3, ZNF316, SMARCA2, ZNF660, XBP1, SRSF4, ZNF596, HNRNPK, ATF3, THRB, ZFP64, HNRNPUL1, RUNX3, CBFB, ZNF273, TP63, MITF, ZNF467, INTS11, MAF, ELF1, RBM39, SNAI2, KLF10, ZNF571, FUS, CTCF, JUN, TAF3, L3MBTL4, ZBTB20, LMO1, MNT, RYBP, DPF2, IRF4, ZNF423, PDX1, TFAP2C, RBPJ, MLX, ZSCAN21, ZBTB17, ZBTB48, ZNF317, NONO, SRF, DDX5, ONECUT1, KDM4A, HOMEZ, TSHZ1, LHX2, FOXP2, ZKSCAN2, RXRA, NKX3-1, PRDM14, MIER3, HNRNPH1, NR3C1, STAT5B, KMT2A, ZBTB11, CCAR2, TBL1XR1, KLF8, GRHL2, EBF3, ZBTB14, NFIL3, THAP11, EZH2phosphoT487, LDB1, SOX13, AFF4, POU4F2, ZNF513, SP3, ARNT, DAXX, BACH1, ZNF48, ZEB2, NFYA, HMBOX1, PBX3, NCAPH2, ZNF10, HMGXB4, TEAD3, ZXDB, U2AF1, TAF7, KLF9, TBX5, USF1, BCL11A, TFAP2A, SP1, ZNF479, ASH2L, CTBP2, PCGF2, GLIS2, PRDM6, SMC3, STAG1, STAG2, ZNF394, TRP47, SAFB, AGO1, MTA3, EBF1, MAFF, ZNF580, ZKSCAN1, KDM1A, BRG1, ISL1, ZIC2, PCGF1, GATA3, KLF15, TAL1, NRIP1, ZNF143, AGO2, CBX2, TP53, NFKB1, ZSCAN22, BRD2, PHF5A, KAT8, TBX21, EGR1, RB1, TFIIIC, RNF2, BRD4, JUND, CUX1, ZSCAN23, TBX2, ZNF468, PGR, FANCL, SOX2, PATZ1, TFAP4, SIN3B, BMI1, CHD7, MXD4, ZNF189, KLF6, NFE2L2, SAP30, ESR1, KLF1, ZNF695, SOX9, E2F6, TRIM24, RFX5, U2AF2, ZNF92, GTF2F1, GLIS1, POU2F2, KDM4C, ZSCAN5A, HIC1, SP4, ERG2, TBP, HNF4G, ETS1, MYC, ARID1B, KLF12, NKX2-1, MCRS1, GABPA, STAT3, IKZF1, DNMT3B, INO80, EZH2, ZNF652, PHF8, SPI1, ZNF202, PCBP1, HDAC2, INTS13, GATAD2B, ZNF76, ETV5, BCL6, SIN3A, ZBTB12, ZFP37, ERG3, CREBBP, ZNF384, RARA, NFYC, TAF15, SMAD4, CDK8, ZEB1, ZMYM3, RBM22, MAFK, HNF4A, REST, ARID1A, ZHX1, HNRNPLL, HOXA9, BCOR, FOXP1, AATF, ZNF34, CXXC4, PPARG, TBL1X, HDAC6, ZNF692, GTF2B, ZNF30, TCF7, ZNF823, FOXO3, RELA, TARDBP, ZNF611, MAX, NR2F1, TCF7L2, KDM5B, RUVBL1, T, AR, YAP1, ZNF324, HEXIM1, ZNF280D, AHR, DMAP1, FOSL2, ZNF391, HMG20A, HMGN3, SUZ12, RBFOX2, ZFHX2, SFMBT1, NFIC, ZNF362, CTCFL, PRDM1, MECOM, CDX2, ZNF629, KLF5, TRIM28, BCLAF1, ETV1, RCOR2, HNF1B, USF2, TCF12, EP300, BAF155, GATA6, PRDM4, SOX6, E2F1, SMC1, TEAD4, FOXA3, ZNF175, EED, CHD8, BRD1, MYCN, CDK7, RUNX1T1, GATAD1, GMEB2, ARID3A, ASCL1, ZNF341, EOMES, RAD21, GRHL3, PROX1, ZNF614, XRCC5, NFE2, TCF25, ZNF639, ZNF750, ZNF501, FEZF1, TRPS1, TFE3, ZNF664, HBP1, IRF1, EHF, SREBF1, ZGPAT, NAB2, MRTFB, PTBP1, CBX1, SMC1A, MAFG, SIRT6, ZNF335, ZFX, FIP1L1, SMAD3, PCBP2, NMYC, CBX8, TWIST1, PRPF4, ZSCAN30, GATA4, OSR2, ZNF184, CDK6, PBX4, NRF1, FOS, CHD1, TGIF2, MED1, CEBPD, MYB, KDM6B, VEZF1, ZNF3, L3MBTL2, NIPBL, ZBTB7A, CCNT2, PHIP, TCF3, SKI, NELFA, ZNF283, FOXA2, RBBP5, ZNF600, MIER2, CDK9, HOXB13, YY1, ZNF148, SP140, HIF1A, OTX2, ZNF519, ZNF449, GATA1, CEBPG, SP7, NR2F2, ZNF213, BHLHE40, NFKBIZ, TAF1, ZBTB40, ZBTB42, MYNN, CLOCK, MAZ, BRCA1
- Target gene symbol (double-evidenced CRMs): CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 5
- Number of somatic mutations (non-coding): 1
- Related genes and loops