- Basic information
- CohesinDB ID: CDBP00413980
- Locus: chr21-17528207-17529568
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Data sourse: GSE67783, ENCSR230ZWH, GSE86191, GSE111913, GSE206145-NatGen2015, ENCSR917QNE
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Cell type: Fibroblast, HCT-116, RT-112, Liver, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
60% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 45%,
"5_TxWk": 31%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZNF384, KLF4, PGR, NR3C1, TEAD3, NCOA3, SCRT2, KLF6, ZFX, RAD21, ELF3, TP63, AGO2, NFIL3, TEAD4, CTCF, RBM22, SP1, AHR, HNF4A
- Target gene symbol (double-evidenced CRMs): CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 25
- Number of somatic mutations (non-coding): 5
- Related genes and loops