- Basic information
- CohesinDB ID: CDBP00413987
- Locus: chr21-17542111-17543488
-
Data sourse: GSE206145-GSE177045, ENCSR230ZWH, GSE72082, ENCSR000BLY, ENCSR150EFU, ENCSR000ECS, ENCSR917QNE, GSE138405, GSE76893, GSE130135, ENCSR000EEG, ENCSR338DUC, ENCSR193NSH, ENCSR768DOX, ENCSR000BLS, GSE206145, ENCSR981FDC, ENCSR247LSH, GSE62063, ENCSR000EHX, ENCSR167MTG, ENCSR853VWZ, ENCSR956LGB, ENCSR335RKQ, ENCSR054FKH, GSE126990, ENCSR748MVX
-
Cell type: MCF-7, RPE, Hela-Kyoto, Hep-G2, HEK293T, A-549, HeLa-S3, SK-N-SH, Liver, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 8% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.878
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
60% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 37%,
"15_Quies": 32%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: NFIA, PGR, ZNF391, HMG20A, ZNF660, SOX2, HNF1A, ZNF101, FOXA1, HLF, RBFOX2, RXRB, KDM3A, TFAP4, TSC22D4, THRB, NFIC, ATF3, BMI1, HNRNPUL1, ZNF362, ZBTB44, PRDM1, IKZF3, CHD7, MXD4, ZNF189, ZSCAN4, HDAC3, CDX2, ZNF629, KLF5, TEAD1, TRIM28, KLF6, ETV1, KLF10, RCOR2, ESR1, HNF1B, PITX3, MBD4, JUN, TCF12, BAF155, EP300, L3MBTL4, SOX5, GATA6, PRDM4, RFX3, KLF3, FOXA3, ZNF175, TEAD4, GATAD2A, PDX1, RBPJ, MLX, GLIS1, NANOG, ZNF263, HHEX, ZSCAN21, ZBTB17, ZNF317, ERF, SRF, GATAD1, SAP130, ARID3A, HIC1, HNF4G, ERG, ZBTB21, ZNF341, MYC, ONECUT1, TSHZ1, HOMEZ, RAD21, ZNF24, RXRA, NKX2-1, GABPA, ZNF614, NKX3-1, RCOR1, MIER3, ZNF639, NR2F6, DNMT3B, TCF25, NR3C1, ESRRA, CEBPB, CREB1, TBL1XR1, KLF8, FEZF1, ZNF652, EBF3, TRPS1, GABPB1, HES1, TFE3, MIXL1, ZNF664, IRF1, HBP1, HDAC2, GATA2, SSRP1, ZNF644, SIX2, DRAP1, ZGPAT, NFIL3, ETV5, RUNX1, THAP11, BCL6, SMC1A, CEBPA, NKX2-2, SOX13, ZFP37, ZNF770, TBX3, CBX8, SP5, SMARCC1, PRDM10, MYBL2, RARA, ZNF384, ZNF35, NFYC, CREBBP, ZSCAN30, GATA4, OSR2, GR, ZNF184, NRF1, ZEB2, ZNF518A, PBX3, ZNF10, SMARCB1, HMGXB4, MED1, TEAD3, ZEB1, ZXDB, SPDEF, SCRT2, PIAS1, ZNF3, NR1H2, MBD1, RBM22, NIPBL, SP1, HNF4A, IKZF5, REST, ARID2, POU2F3, ASH2L, PHIP, FOXP1, PRDM6, SMC3, ZNF34, ETV4, ZNF394, SKI, PPARG, FOXA2, CREM, CHD2, MIER2, ZNF692, WT1, FOXF1, ZNF574, ZBTB33, TCF7, HOXB13, ZNF580, FOXO3, KDM1A, YY1, AHR, BRG1, GATA3, TAL1, MAX, GATA1, AGO2, HAND2, CBX2, TLE3, KLF4, CEBPG, SP7, GFI1B, NR2F2, TCF7L2, PKNOX1, ZNF213, PHOX2B, PHF5A, ELF3, KAT8, ZNF843, ARID4B, AR, NFKBIZ, BHLHE40, ZNF324, ZNF366, MAML3, EGR1, ZBTB26, BRD4, JUND, MAZ, ZSCAN23, SMAD4.1D12, BRCA1, DMAP1, FOSL2
- Target gene symbol (double-evidenced CRMs): CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 45
- Number of somatic mutations (non-coding): 0
- Related genes and loops