- Basic information
- CohesinDB ID: CDBP00413988
- Locus: chr21-17548224-17548770
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Data sourse: GSE138405, GSE111913, GSE67783, GSE68388
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Cell type: RT-112, Hela-Kyoto, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,SA2,SMC1
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
60% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 35%,
"5_TxWk": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFIA, PGR, HMG20A, HNF1A, FOXA1, RXRB, KDM3A, TFAP4, HNRNPK, NFIC, MXD4, ZNF189, HDAC3, ZNF467, TEAD1, KLF6, SNAI2, RCOR2, ESR1, JUN, CTCF, BAF155, EP300, L3MBTL4, MNT, SOX5, GATA6, PRDM4, RFX3, FOXA3, ZNF175, GATAD2A, PDX1, TFAP2C, RBPJ, MLX, GLIS1, POU2F2, CHD8, NANOG, BRD3, HHEX, TOP2A, CTBP1, ZSCAN21, GATAD1, SAP130, ARID3A, HIC1, ZNF300, ERG, HNF4G, SMARCC2, ETS1, MYC, ONECUT1, HOMEZ, RAD21, RXRA, NKX2-1, FOXK2, GABPA, STAT3, ZNF614, XRCC5, NKX3-1, MIER3, NR2F6, ZNF639, ARNTL, VDR, NR3C1, ESRRA, CEBPB, HNRNPL, CREB1, EZH2, TBL1XR1, KLF8, GRHL2, ZNF652, TRPS1, GABPB1, SPI1, MIXL1, HBP1, TFE3, IRF1, HDAC2, GATA2, SSRP1, ZNF644, DRAP1, ZGPAT, ZNF766, NFIL3, NCOA2, ETV5, RUNX1, THAP11, SMC1A, BCL6, CEBPA, CBX1, FIP1L1, ZFX, SIN3A, SOX13, SMAD3, PCBP2, ZFP37, TBX3, CBX8, SP5, SMARCC1, MYBL2, RARA, CREBBP, GATA4, OSR2, ARNT, PBX4, ZNF48, SMAD4, FOXM1, FOS, CDK8, HMGXB4, TGIF2, MED1, TEAD3, PIAS1, ZMYM3, ZNF3, MBD1, RBM22, MAFK, SP1, NIPBL, TFAP2A, HNF4A, IKZF5, ASH2L, PHIP, FOXP1, SMC3, STAG1, ETV4, SKI, PPARG, FOXA2, CREM, MIER2, MAFF, WT1, ZBTB33, TCF7, HOXB13, ZNF580, FOXO3, KDM1A, YY1, RELA, SP140, HIF1A, GATA3, MAX, NRIP1, ZNF143, AGO2, CBX2, TLE3, CEBPG, KLF4, SP7, NCOA3, NR2F2, NR2F1, TCF7L2, KDM5B, PKNOX1, NFKB1, BRD2, ELF3, KAT8, PHF5A, ARID4B, AR, NFKBIZ, TAF1, ZNF579, BHLHE40, EGLN2, ZBTB26, NOTCH3, BRD4, JUND, CLOCK, CUX1, ZNF24, AHR, FOSL2
- Target gene symbol (double-evidenced CRMs): CXADR
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 20
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154639,
- Related loop:
chr21:16925000-16950000~~chr21:17525000-17550000,
chr21:16925000-16950000~~chr21:17550000-17575000,
chr21:17050000-17075000~~chr21:17550000-17575000,
chr21:17100000-17125000~~chr21:17550000-17575000,
chr21:17375000-17400000~~chr21:17550000-17575000,
chr21:17385997-17387993~~chr21:17553561-17555852,
chr21:17386011-17388740~~chr21:17553679-17555816,
chr21:17386038-17389021~~chr21:17553442-17555850,
chr21:17386054-17389016~~chr21:17553561-17555841,
chr21:17386118-17388987~~chr21:17553707-17555628,
chr21:17400000-17425000~~chr21:17550000-17575000,
chr21:17425000-17450000~~chr21:17550000-17575000,
chr21:17550000-17575000~~chr21:17650000-17675000,