- Basic information
- CohesinDB ID: CDBP00415162
- Locus: chr21-25036675-25037042
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Data sourse: GSE103477, GSE50893
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Cell type: GM19240, THP-1, GM12891
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
31% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 92%,
"9_Het": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SMC1A, CHD8, SOX2, XBP1, GTF2B, CDK9, ERG, ZNF19, MYC, RAD21, TCF4, GRHL3, GABPA, SPIB, CDK8, ZNF736, VDR, KMT2A, EZH2, OCA2, CTCF, SPI1, AR, BRD4, NCOR2
- Target gene symbol (double-evidenced CRMs): ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154734,
- Related loop:
chr21:18275000-18300000~~chr21:25025000-25050000,
chr21:21000000-21025000~~chr21:25025000-25050000,
chr21:22775000-22800000~~chr21:25025000-25050000,
chr21:23125000-23150000~~chr21:25025000-25050000,
chr21:23400000-23425000~~chr21:25025000-25050000,
chr21:24575000-24600000~~chr21:25025000-25050000,
chr21:24593668-24594925~~chr21:25038973-25040738,
chr21:24875000-24900000~~chr21:25025000-25050000,
chr21:24894830-24897390~~chr21:25038993-25040888,
chr21:24894830-24897394~~chr21:25039002-25040942,
chr21:24895217-24897409~~chr21:25038938-25040859,
chr21:24895257-24897346~~chr21:25038912-25040890,
chr21:24895308-24897338~~chr21:25038912-25040868,
chr21:24895404-24897444~~chr21:25038898-25041036,
chr21:24895412-24897320~~chr21:25039014-25040785,
chr21:24895412-24897374~~chr21:25038926-25041026,
chr21:24895431-24897310~~chr21:25038859-25040781,
chr21:24895431-24897366~~chr21:25038878-25040962,
chr21:24895436-24897312~~chr21:25038928-25040817,
chr21:24895439-24897330~~chr21:25039058-25040813,
chr21:24895469-24897373~~chr21:25039058-25040876,
chr21:24895473-24897247~~chr21:25039094-25040627,
chr21:24895510-24897368~~chr21:25038960-25041269,
chr21:24895560-24897204~~chr21:25038968-25040820,
chr21:24895665-24896948~~chr21:25039050-25040629,
chr21:24895738-24897210~~chr21:25038968-25040729,
chr21:25025000-25050000~~chr21:25175000-25200000,
chr21:25025000-25050000~~chr21:25250000-25275000,
chr21:25025000-25050000~~chr21:25300000-25325000,
chr21:25025000-25050000~~chr21:25350000-25375000,
chr21:25025000-25050000~~chr21:25375000-25400000,
chr21:25025000-25050000~~chr21:26825000-26850000,
chr21:25038878-25040962~~chr21:25384794-25387223,
chr21:25038898-25041036~~chr21:25312967-25315286,
chr21:25038960-25041269~~chr21:25312968-25315386,
chr21:25038960-25041269~~chr21:25384420-25387034,
chr21:25039015-25040833~~chr21:25282963-25284708,