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Basic information

CohesinDB ID: CDBP00415163

Locus: chr21-25039299-25040740

Data sourse: ENCSR000BLD, GSE206145-GSE177045, ENCSR230ZWH, GSE72082, GSE126634, GSE116868, ENCSR000BLY, ENCSR404BPV, GSE105028, GSE103477, GSE111537, GSE25021, GSE108869, ENCSR917QNE, ENCSR000EFJ, ENCSR000BTU, GSE139435, ENCSR000DZP, ENCSR000EAC, GSE93080, GSE138405, GSE76893, GSE101921, GSE152721, GSE206145-NatGen2015, ENCSR198ZYJ, GSE138105, ENCSR703TNG, GSE106870, GSE116344, GSE145327, ENCSR000EEG, ENCSR000EHW, GSE206145, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, ENCSR635OSG, GSE97394, GSE55407, ENCSR000BTQ, ENCSR000HPG, GSE155324, ENCSR000EDE, GSE126990, GSE50893, ENCSR000ECS, GSE131577

Cell type: MDM, RH4, GM10847, GM2610, SLK, CVB-hiPSC, GM19240, Liver, B-cell, H9-hESC, GM2630, Fibroblast, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, GM18486, GM18526, H1-hESC, SNYDER, GM18505, Leukemia-SEM, MB157, Lymphoblast, GM12878, GM12891, GM2588, SK-N-SH, GM19239, GM19193, HAP1, GM19099, HUES64, MCF-7, GM12892, THP-1, Hela-Kyoto, HL-60, MCF-10A, Hep-G2, Neurons-H1, GM19238, OCI-AML-3, GM18951

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 29% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.500

Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: True

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 31% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 74%, "7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, CBX5, XBP1, FOXA1, NFIC, RUNX3, JMJD1C, ELF1, BCLAF1, ZNF217, ESR1, OCA2, CTCF, JUN, PAX8, TRIM24, IRF4, SMC1, KMT2B, PDX1, POU2F2, NANOG, TOP2A, MTA2, SRF, MLLT3, SP4, ERG, MYC, RAD21, NKX2-1, GABPA, STAT3, IKZF1, RCOR1, ARNTL, KMT2A, SPI1, EHF, RELB, BCL6, SMC1A, NKX2-2, ZNF654, TRIM22, MEF2A, CREBBP, ZNF384, ZBTB2, PBX4, ARNT, ATF2, FOS, CDK8, MED1, TERF1, NIPBL, BCL11A, ATF7, SMC3, STAG2, STAG1, MLLT1, MEF2B, FOXA2, MEF2C, CDK9, KDM1A, YY1, TARDBP, JUNB, TCF4, SKIL, HIF1A, OTX2, BATF, SPIB, KDM5B, PHOX2B, ELF3, TBX21, AR, TAF1, IKZF2, BRD4

Target gene symbol (double-evidenced CRMs): ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154734,

eachgene

Deatailed information for cohesin site CDBP00415163