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Basic information

CohesinDB ID: CDBP00415204

Locus: chr21-25327956-25328178

Data sourse: GSE206145-NatGen2015, GSE67783

Cell type: Fibroblast, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA1,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 89%, "5_TxWk": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, CHD8, SMARCA2, FOXA2, EZH2phosphoT487, SIN3A, ZFX, XBP1, ZBTB48, WT1, SMAD3, ZBTB33, TWIST1, ERG, MEF2A, RELA, HOXC5, YY1, NEUROD1, JUNB, NFIC, ATF3, GATA4, RUNX2, CHD7, SP140, LHX2, PBX4, HIF1A, RXRA, OTX2, GATA3, NKX2-1, GABPA, HMGB2, STAT3, PBX3, FOXM1, MAX, FOS, ZNF143, RCOR1, MED1, ARNTL, NR3C1, CEBPB, KLF4, SPDEF, CEBPD, TEAD1, ELF1, EZH2, TP53, NFKB1, EBF3, PHOX2B, CTCF, TCF12, ZHX2, EP300, USF1, JUN, EHF, AR, BHLHE40, MAFK, TAF1, BRD2, GATA2, REST, RFX5, FLI1, BRD4, JUND, MRTFB, TEAD4, MYF5, FOSL2

Target gene symbol (double-evidenced CRMs): APP,MRPL39

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000142192,

eachgene

Deatailed information for cohesin site CDBP00415204