Deatailed information for gene ENSG00000154719
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00009790
- Gene Symbol: MRPL39
- Ensembl ID: ENSG00000154719
-
Gene locus: chr21:25585655-25607517
Strand: -
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-23975217-23975960,
chr21-23977792-23978602,
chr21-23978887-23979856,
chr21-23996763-23997066,
chr21-23997634-23997943,
chr21-25324462-25325130,
chr21-25327956-25328178,
chr21-25328669-25330433,
chr21-25342463-25343340,
chr21-25349180-25349255,
chr21-25349636-25351281,
chr21-25399514-25400754,
chr21-25401827-25402550,
chr21-25420705-25426209,
chr21-25576227-25589346,
chr21-25589610-25591105,
chr21-25591791-25592728,
chr21-25595802-25596358,
chr21-25600851-25601124,
chr21-25606719-25610187,
chr21-25638808-25641127,
chr21-25699316-25700064,
chr21-25700379-25701188,
chr21-25706599-25710241,
chr21-25714159-25714449,
chr21-25717358-25718663,
chr21-25721623-25722022,
chr21-25731829-25732870,
chr21-25733103-25733519,
chr21-25733724-25736727,
chr21-25750080-25750495,
chr21-25756342-25756628,
chr21-25770235-25770898,
chr21-25800560-25802279,
chr21-25808496-25808560,
chr21-25811673-25811983,
chr21-25812539-25812961,
chr21-25819579-25819720,
chr21-25820184-25820530,
chr21-25824592-25824953,
chr21-25828364-25828688,
chr21-25833846-25834090,
chr21-25835857-25837162,
chr21-25837509-25838288,
chr21-25838795-25839584,
chr21-25846197-25846384,
chr21-25848451-25849082,
chr21-25850382-25850871,
chr21-25857068-25857674,
chr21-25862118-25863437,
chr21-25865445-25866261,
chr21-25866908-25867564,
chr21-25868924-25869531,
chr21-25871333-25873005,
chr21-25875158-25875785,
chr21-25877272-25877556,
chr21-25878883-25884507,
chr21-25886456-25886884,
chr21-25887111-25887606,
chr21-25887958-25888558,
chr21-25890135-25890660,
chr21-25895168-25897778,
chr21-25898579-25899047,
chr21-25982956-25984253,
chr21-25986015-25986347,
chr21-25988529-25989413,
chr21-25991403-25991747,
chr21-25992093-25992403,
chr21-25997796-25999512,
chr21-25999972-26000170,
chr21-26000893-26001794,
chr21-26003541-26003718,
chr21-26007390-26008630,
chr21-26008836-26009076,
chr21-26009756-26011796,
chr21-26012489-26013187,
chr21-26014050-26014288,
chr21-26015969-26016331,
chr21-26016609-26017229,
chr21-26019797-26021009,
chr21-26022497-26023913,
chr21-26076786-26077083,
chr21-26077573-26077818,
chr21-26081211-26081885,
chr21-26082626-26082861,
chr21-26084181-26084592,
chr21-26085937-26086198,
chr21-26091586-26092080,
chr21-26093188-26093377,
chr21-26094937-26095373,
chr21-26097068-26098116,
chr21-26099539-26100826,
chr21-26150217-26150652,
chr21-26151334-26152383,
chr21-26153595-26154542,
chr21-26154777-26155253,
chr21-26158881-26159268,
chr21-26159924-26160609,
chr21-26162072-26162427,
chr21-26162939-26163160,
chr21-26163946-26164899,
chr21-26165409-26165563,
chr21-26165938-26172090,
chr21-26172443-26173621,
chr21-26176450-26178042,
chr21-26179380-26179859,
chr21-26181756-26182144,
chr21-26184190-26184559,
chr21-26184891-26185848,
chr21-26189728-26190051,
chr21-26192241-26192738,
chr21-26194214-26195543,
chr21-26196483-26196948,
chr21-26197472-26197568,
chr21-26199145-26200151,
chr21-26330958-26332551,
chr21-26333724-26334264,
chr21-26341128-26341398,
chr21-26375270-26375569,
chr21-26377212-26377465,
chr21-26385630-26386225,
chr21-26388039-26392190,
chr21-26489802-26491360,
chr21-26491759-26492502,
chr21-26499281-26499944,
chr21-26527113-26527235,
chr21-26529571-26529884,
chr21-26542226-26542363,
chr21-26543512-26543793,
chr21-26545511-26545777,
chr21-26546651-26547189,
chr21-26587292-26589031,
chr21-26593914-26594194,
chr21-26618621-26618916,
chr21-26620866-26621001,
chr21-26624988-26625410,
chr21-26702109-26702704,
chr21-26709227-26709736,
chr21-26714761-26718662,
chr21-26718980-26720367,
chr21-26721013-26721255,
chr21-26721627-26722108,
chr21-26731078-26733640,
chr21-26737504-26738146,
chr21-26747114-26747560,
chr21-26748116-26748489,
chr21-26801063-26801912,
chr21-26805125-26805692,
chr21-26806617-26807296,
chr21-26810912-26811585,
chr21-26814123-26815116,
chr21-26815437-26816621,
chr21-26816961-26817766,
chr21-26819112-26820624,
chr21-26824624-26825033,
chr21-26826754-26827193,
chr21-26832682-26836085,
chr21-26836642-26836862,
chr21-26837135-26838300,
chr21-26839542-26841526,
chr21-26841743-26847812,
chr21-26848196-26852813,
-
Co-expression with cohesin genes Rho = 0.5742
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.236
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.890
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,TAMR-MCF7,MB157,DU145,Keratinocytes192627,GM12892,K1,hTERT-HME1,H1-Mesenchymal,H1-Mesendoderm,Olfactory,Hepatocyte-H9,GM19239,HEK293T,MCF-7,GM12891,SARS-Cov2-olfactory,GM12878,MSiPS,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,LNCaP,SU-DHL-2,H9-hESC,KU-19-19,Primed-hESC,iPSC,Liver,ARPE-19,REC-1,Hep-G2,HT-1197,Kelly,H1-hESC,HCC1599,GM19238,HT-1376,Motor-Neuron,MSLCL,NaiveB,U-937,HUES64,SU-DHL-4,CyT49-hESC,HUVEC,HL-60,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,Jurkat,CyT49-Gut,CC-2551,HAP1,HFF-hTERT,MCF7-FASR
- Related loop:
chr21:23975000-24000000~~chr21:25575000-25600000,
chr21:25325000-25350000~~chr21:25575000-25600000,
chr21:25400000-25425000~~chr21:25575000-25600000,
chr21:25400000-25425000~~chr21:25600000-25625000,
chr21:25420529-25422993~~chr21:25606735-25609548,
chr21:25420540-25423403~~chr21:25606733-25609495,
chr21:25420779-25423371~~chr21:25606803-25609752,
chr21:25420881-25422831~~chr21:25606865-25609546,
chr21:25421193-25422730~~chr21:25606816-25609496,
chr21:25575000-25600000~~chr21:25700000-25725000,
chr21:25575000-25600000~~chr21:25750000-25775000,
chr21:25575000-25600000~~chr21:26150000-26175000,
chr21:25575000-25600000~~chr21:26175000-26200000,
chr21:25575000-25600000~~chr21:26375000-26400000,
chr21:25575000-25600000~~chr21:26800000-26825000,
chr21:25575000-25600000~~chr21:28950000-28975000,
chr21:25600000-25625000~~chr21:25700000-25725000,
chr21:25600000-25625000~~chr21:25725000-25750000,
chr21:25600000-25625000~~chr21:25750000-25775000,
chr21:25600000-25625000~~chr21:25800000-25825000,
chr21:25600000-25625000~~chr21:25825000-25850000,
chr21:25600000-25625000~~chr21:25850000-25875000,
chr21:25600000-25625000~~chr21:25875000-25900000,
chr21:25600000-25625000~~chr21:25975000-26000000,
chr21:25600000-25625000~~chr21:26000000-26025000,
chr21:25600000-25625000~~chr21:26075000-26100000,
chr21:25600000-25625000~~chr21:26150000-26175000,
chr21:25600000-25625000~~chr21:26175000-26200000,
chr21:25600000-25625000~~chr21:26325000-26350000,
chr21:25600000-25625000~~chr21:26375000-26400000,
chr21:25600000-25625000~~chr21:26475000-26500000,
chr21:25600000-25625000~~chr21:26525000-26550000,
chr21:25600000-25625000~~chr21:26575000-26600000,
chr21:25600000-25625000~~chr21:26600000-26625000,
chr21:25600000-25625000~~chr21:26700000-26725000,
chr21:25600000-25625000~~chr21:26725000-26750000,
chr21:25600000-25625000~~chr21:26825000-26850000,
chr21:25600000-25625000~~chr21:27700000-27725000,
chr21:25600000-25625000~~chr21:28050000-28075000,
chr21:25600000-25625000~~chr21:28325000-28350000,
chr21:25600000-25625000~~chr21:28725000-28750000,
chr21:25606634-25609370~~chr21:25707698-25709437,
chr21:25606634-25609370~~chr21:25734065-25736120,
chr21:25606634-25609370~~chr21:25800840-25802441,
chr21:25606701-25609531~~chr21:25707358-25710489,
chr21:25606733-25609495~~chr21:25639158-25640825,
chr21:25606733-25609495~~chr21:25707675-25710605,
chr21:25606735-25609548~~chr21:25638240-25641048,
chr21:25606735-25609548~~chr21:25707427-25710615,
chr21:25606735-25609548~~chr21:25733753-25735837,
chr21:25606735-25609548~~chr21:25800672-25802523,
chr21:25606735-25609548~~chr21:25871125-25872823,
chr21:25606746-25609376~~chr21:25707582-25709297,
chr21:25606776-25609578~~chr21:25707372-25710258,
chr21:25606776-25609578~~chr21:25734027-25737101,
chr21:25606776-25609578~~chr21:25861792-25863529,
chr21:25606787-25609495~~chr21:25734193-25735774,
chr21:25606789-25609441~~chr21:25707688-25710567,
chr21:25606789-25609441~~chr21:25800789-25802399,
chr21:25606789-25609441~~chr21:25861500-25863573,
chr21:25606790-25609462~~chr21:25639349-25640533,
chr21:25606790-25609462~~chr21:25707708-25709351,
chr21:25606798-25609451~~chr21:25639345-25640775,
chr21:25606798-25609451~~chr21:25707713-25709464,
chr21:25606798-25609451~~chr21:25733716-25736049,
chr21:25606798-25609451~~chr21:25800850-25802423,
chr21:25606803-25609752~~chr21:25707420-25710495,
chr21:25606803-25609752~~chr21:25733690-25736009,
chr21:25606803-25609752~~chr21:25800750-25802769,
chr21:25606803-25609752~~chr21:25861575-25863761,
chr21:25606809-25609470~~chr21:25707720-25709296,
chr21:25606813-25609482~~chr21:25707421-25709301,
chr21:25606813-25609514~~chr21:25707387-25710588,
chr21:25606813-25609514~~chr21:25734223-25736000,
chr21:25606813-25609514~~chr21:25800897-25802448,
chr21:25606813-25609539~~chr21:25707400-25709389,
chr21:25606813-25609539~~chr21:25734172-25735871,
chr21:25606813-25609539~~chr21:25800628-25802675,
chr21:25606813-25609539~~chr21:26168567-26171752,
chr21:25606813-25609564~~chr21:25639067-25640965,
chr21:25606813-25609564~~chr21:25707391-25709523,
chr21:25606813-25609564~~chr21:25734147-25737065,
chr21:25606813-25609564~~chr21:26168596-26171705,
chr21:25606815-25609560~~chr21:25707341-25710526,
chr21:25606815-25609560~~chr21:25800749-25802528,
chr21:25606815-25609560~~chr21:25861600-25863597,
chr21:25606816-25609496~~chr21:25707510-25709485,
chr21:25606816-25609496~~chr21:25800839-25802465,
chr21:25606816-25609496~~chr21:25861723-25863498,
chr21:25606818-25609406~~chr21:25707731-25709697,
chr21:25606818-25609406~~chr21:25734212-25736761,
chr21:25606824-25609539~~chr21:25707688-25710613,
chr21:25606824-25609539~~chr21:25800789-25802467,
chr21:25606830-25609546~~chr21:25707223-25709539,
chr21:25606832-25609355~~chr21:25734228-25736011,
chr21:25606834-25609470~~chr21:25707558-25709528,
chr21:25606834-25609470~~chr21:25733847-25735307,
chr21:25606843-25609485~~chr21:25733632-25735523,
chr21:25606865-25609546~~chr21:25707695-25710621,
chr21:25606869-25609453~~chr21:25707877-25710598,
chr21:25606871-25609531~~chr21:25707660-25710535,
chr21:25606871-25609531~~chr21:25800793-25802413,
chr21:25606871-25609531~~chr21:25861792-25863454,
chr21:25606873-25609559~~chr21:25707322-25709495,
chr21:25606873-25609559~~chr21:25800683-25802517,
chr21:25606873-25609559~~chr21:25861596-25863488,
chr21:25606880-25609493~~chr21:25707645-25709314,
chr21:25606884-25609585~~chr21:25800975-25802409,
chr21:25606885-25609476~~chr21:25707878-25709259,
chr21:25606887-25609611~~chr21:25708003-25709470,
chr21:25606887-25609611~~chr21:25800900-25802671,
chr21:25606887-25609611~~chr21:25861935-25863735,
chr21:25606889-25609464~~chr21:25734236-25735414,
chr21:25606894-25609602~~chr21:25708009-25709440,
chr21:25606899-25609820~~chr21:25639037-25640766,
chr21:25606899-25609820~~chr21:25707427-25709461,
chr21:25606899-25609820~~chr21:25800780-25802528,
chr21:25606899-25609820~~chr21:25861786-25863545,
chr21:25606914-25609560~~chr21:25871146-25873235,
chr21:25606914-25609560~~chr21:26000712-26002239,
chr21:25606920-25609321~~chr21:25734731-25735901,
chr21:25606920-25609753~~chr21:25708007-25709432,
chr21:25606920-25609753~~chr21:25800965-25802415,
chr21:25606927-25609505~~chr21:25708020-25709433,
chr21:25606943-25609746~~chr21:25708004-25709487,
chr21:25606943-25609746~~chr21:25801005-25802520,
chr21:25606943-25609746~~chr21:25861950-25863530,
chr21:25606945-25609755~~chr21:25708023-25709409,
chr21:25606945-25609755~~chr21:25861950-25863417,
chr21:25606952-25609468~~chr21:25707804-25709308,
chr21:25606963-25609577~~chr21:25707939-25710591,
chr21:25606981-25609372~~chr21:25707950-25709246,
chr21:25606981-25609574~~chr21:25707674-25709566,
chr21:25607003-25609546~~chr21:25862121-25863346,
chr21:25607005-25609570~~chr21:25800875-25802516,
chr21:25607005-25609570~~chr21:25861550-25863545,
chr21:25607045-25609461~~chr21:25707835-25709504,
chr21:25607052-25609346~~chr21:25707738-25709299,
chr21:25607533-25609506~~chr21:25862107-25863351,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQYQWPF5, GSE95015, GSE43070, 4DNFIDJ2JZ7Q, 4DNFITUOMFUQ, ENCSR794RDS, ENCSR852KQC, ENCSR361AYD, 4DNFIDSWKFF5, GSE103148, 4DNFI7H4II2V, 4DNFIZ4F74QR, ENCSR350NJV, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, ENCSR113OIR, 4DNFIKYXMF1E, 4DNFIRKGMZRQ, GSE99541, ENCSR668RDP, 4DNFIL5K3MA1, GSE97394, 4DNFICEGAHRC, 4DNFIE8T8JZ8, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, ENCSR658RQQ, ENCSR299VMZ, 4DNFI6XD6JAQ, 4DNFISPUVQHA, 4DNFIK61ILGM, GSE108869, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, ENCSR000FDB, ENCSR527RXH, GSE105028, 4DNFIBKZK63V, ENCSR033GUP, 4DNFIQWD8ZYD, ENCSR662QKG, GSE94872, GSE118716, ENCSR499RVD, 4DNFIB7QTIMH, GSE126792, ENCSR146FPM, ENCSR478BMT, GSE69643, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR587DSF, ENCSR452NHL, 4DNFIIMZB6Y9, GSE80820, GSE52457, 4DNFIBT4EAKN, Direct, ENCSR314HAC, ENCSR479MTN, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, ENCSR778FXH, 4DNFI9ZWZ5BS, 4DNFI2J1ODWB, 4DNFIVJ3IIQL, 4DNFIQ2687RT, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIS5F6EBL, 4DNFIZGCA8AH, 4DNFIH7TH4MF, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFIBRSIPE4, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, GSE84022, 4DNFIPV5KFMK, ENCSR672RHL, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIBM714BP, 4DNFIF2D3TL9, 4DNFIFHU75I5, 4DNFIYD8LO9Z, ENCSR444BAR, 4DNFIL9M97T2, ENCSR550JLK, 4DNFI3A3VYWU, 4DNFIJ7OAIFQ, 4DNFIX4PJKXZ, GSE165038, 4DNFIALNLR78, 4DNFIYDBBSE3, ENCSR386KHY, ENCSR379CII, 4DNFIEJEFCAM, ENCSR393LOP, GSE44267, 4DNFIPAF4PYT, GSE48592, ENCSR255XYX, ENCSR404HWQ, 4DNFIE5TEYK7, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR933UZH, ENCSR094EIC, GSE58752, GSE116869, 4DNFI8649RQJ, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, ENCSR545YBD, 4DNFIILDWK8M, ENCSR866FWQ, 4DNFI6EIFUZI, 4DNFII6AN691, GSE131580, ENCSR381DCY, ENCSR981FNA, 4DNFIV239W4L, ENCSR752QCX, ENCSR128RPG, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, GSE101921, ENCSR228TUX, 4DNFI8JFOAJT, 4DNFIOCW5AEM, 4DNFIC3HAU11, 4DNFIQVMVRP6, ENCSR247RGI, ENCSR110JOO, ENCSR338WUS, 4DNFI5LCW273, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM, 4DNFIVSCH2CH
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: K-562,U2OS,SLK,P3HR-1
- Cohesin-DEGs, number of studies: 4
- Cohesin-DEGs, study: GSE140651,GSE138937,GSE131448,GSE89799
- Cohesin-DEGs, subunit: CTCF,SMC1,Rad21,SA2