- Basic information
- CohesinDB ID: CDBP00415289
- Locus: chr21-25700379-25701188
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Data sourse: ENCSR000BTQ, GSE206145-GSE177045, GSE67783, GSE72082, ENCSR703TNG, GSE25021
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Cell type: MCF-7, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 4% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
61% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 62%,
"5_TxWk": 27%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PAX7, PGR, CBX1, ZNF316, ZNF496, FOXA2, SIN3A, TEAD4, ZNF317, FOXA1, CDK9, HOXB13, ERG, MEF2A, RELA, CREBBP, HNRNPK, ZNF384, ZNF585B, JUNB, AHR, RUNX2, MYC, RAD21, RUNX3, PBX4, HIF1A, ARNT, PRDM1, NKX2-1, GATA3, RXRA, GABPA, SMARCE1, STAT3, MAFB, NRIP1, IKZF1, TERF2, MED1, NR3C1, ESRRA, NR2F2, TRIM28, TEAD1, MYB, TCF7L2, CREB1, KDM5B, ZNF217, ESR1, ELF1, GRHL2, TRPS1, GABPB1, JUN, TCF12, ZHX2, EP300, TFAP2A, SPI1, MNT, AR, BRD2, ELF3, ZNF579, DPF2, GATA2, E4F1, EGLN2, RFX5, IRF4, ZNF366, PRKDC, RNF2, BRD4, ZNF280A, NCOA2, ZNF24, EHMT2, TFAP2C
- Target gene symbol (double-evidenced CRMs): JAM2,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 9
- Number of somatic mutations (non-coding): 3
- Related genes and loops