Deatailed information for gene ENSG00000154721
Check detailed explainations here
- Basic information
- CohesinDB ID: CDBG00009791
- Gene Symbol: JAM2
- Ensembl ID: ENSG00000154721
-
Gene locus: chr21:25639257-25717562
Strand: +
- Gene type: protein_coding
- Double-evidenced cohesin related CRMs
- Whether cohesin-related CRMs (double-evidenced): True
- All evidenced type: Interaction,DEGs,
- Regulatory cohesin (double-evidenced):
chr21-25103797-25104160,
chr21-25107468-25108444,
chr21-25399514-25400754,
chr21-25401827-25402550,
chr21-25420705-25426209,
chr21-25426619-25427030,
chr21-25427747-25428210,
chr21-25428548-25429008,
chr21-25434009-25434368,
chr21-25439742-25439939,
chr21-25450123-25450517,
chr21-25451270-25452779,
chr21-25453162-25454024,
chr21-25456209-25458906,
chr21-25459433-25460303,
chr21-25461860-25462035,
chr21-25462477-25463122,
chr21-25463688-25465068,
chr21-25466894-25467363,
chr21-25467956-25468249,
chr21-25473521-25474086,
chr21-25572281-25575261,
chr21-25576227-25589346,
chr21-25589610-25591105,
chr21-25591791-25592728,
chr21-25595802-25596358,
chr21-25600851-25601124,
chr21-25606719-25610187,
chr21-25614176-25615182,
chr21-25624549-25624749,
chr21-25638808-25641127,
chr21-25642332-25642777,
chr21-25646355-25647152,
chr21-25647707-25648230,
chr21-25652526-25652691,
chr21-25658229-25659074,
chr21-25660159-25660645,
chr21-25664270-25664549,
chr21-25670626-25671144,
chr21-25675067-25675600,
chr21-25682530-25682914,
chr21-25688378-25688954,
chr21-25691774-25692309,
chr21-25695469-25696387,
chr21-25697882-25698059,
chr21-25699316-25700064,
chr21-25700379-25701188,
chr21-25706599-25710241,
chr21-25714159-25714449,
chr21-25717358-25718663,
chr21-25721623-25722022,
chr21-25731829-25732870,
chr21-25733103-25733519,
chr21-25733724-25736727,
chr21-25778080-25778847,
chr21-25779288-25779695,
chr21-25787871-25788223,
chr21-25788822-25789364,
chr21-25789892-25791705,
chr21-25795113-25795355,
chr21-25800560-25802279,
chr21-26150217-26150652,
chr21-26151334-26152383,
chr21-26153595-26154542,
chr21-26154777-26155253,
chr21-26158881-26159268,
chr21-26159924-26160609,
chr21-26162072-26162427,
chr21-26162939-26163160,
chr21-26163946-26164899,
chr21-26165409-26165563,
chr21-26165938-26172090,
chr21-26172443-26173621,
chr21-26527113-26527235,
chr21-26529571-26529884,
chr21-26542226-26542363,
chr21-26543512-26543793,
chr21-26545511-26545777,
chr21-26546651-26547189,
chr21-26824624-26825033,
chr21-26826754-26827193,
chr21-26832682-26836085,
chr21-26836642-26836862,
chr21-26837135-26838300,
chr21-26839542-26841526,
chr21-26841743-26847812,
chr21-26848196-26852813,
chr21-26934483-26934858,
chr21-26937952-26938250,
chr21-26938947-26942644,
chr21-26943437-26944214,
chr21-26945787-26946495,
chr21-26946875-26947679,
chr21-26948229-26948588,
chr21-26949868-26950099,
-
Co-expression with cohesin genes Rho = 0.4867
FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)
- Tissue specificity
-
Gene expression across tissues (TPM):
-
Tissue specificity of gene (Gini-coefficient): 0.374
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60
-
Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.882
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90
- Cohesin-loop evidence
- Whether has cohesin-loop: True
-
Involved cell types for loop evidence: H9-endodermal,IMR-90,MCF-10A,MB157,DU145,Keratinocytes192627,GM12892,K1,hTERT-HME1,H1-Mesenchymal,Olfactory,Hepatocyte-H9,GM19239,HEK293T,MCF-7,GM12891,SARS-Cov2-olfactory,GM12878,K-562,A-549,CyT49-pancreatic,HFFc6,PAEC,HeLa-S3,SU-DHL-2,H9-hESC,KU-19-19,iPSC,Liver,ARPE-19,REC-1,Hep-G2,HT-1197,Kelly,H1-hESC,HCC1599,GM19238,HT-1376,Motor-Neuron,MSLCL,HUES64,SU-DHL-4,CyT49-hESC,HUVEC,NPC-H9,CyT49-endoderm,RT-112,Skin-Fibroblast,Jurkat,CC-2551,HFF-hTERT,HAP1
- Related loop:
chr21:25100000-25125000~~chr21:25700000-25725000,
chr21:25400000-25425000~~chr21:25700000-25725000,
chr21:25425000-25450000~~chr21:25700000-25725000,
chr21:25450000-25475000~~chr21:25700000-25725000,
chr21:25575000-25600000~~chr21:25700000-25725000,
chr21:25600000-25625000~~chr21:25700000-25725000,
chr21:25606634-25609370~~chr21:25707698-25709437,
chr21:25606701-25609531~~chr21:25707358-25710489,
chr21:25606733-25609495~~chr21:25639158-25640825,
chr21:25606733-25609495~~chr21:25707675-25710605,
chr21:25606735-25609548~~chr21:25638240-25641048,
chr21:25606735-25609548~~chr21:25707427-25710615,
chr21:25606746-25609376~~chr21:25707582-25709297,
chr21:25606776-25609578~~chr21:25707372-25710258,
chr21:25606789-25609441~~chr21:25707688-25710567,
chr21:25606790-25609462~~chr21:25639349-25640533,
chr21:25606790-25609462~~chr21:25707708-25709351,
chr21:25606798-25609451~~chr21:25639345-25640775,
chr21:25606798-25609451~~chr21:25707713-25709464,
chr21:25606803-25609752~~chr21:25707420-25710495,
chr21:25606809-25609470~~chr21:25707720-25709296,
chr21:25606813-25609482~~chr21:25707421-25709301,
chr21:25606813-25609514~~chr21:25707387-25710588,
chr21:25606813-25609539~~chr21:25707400-25709389,
chr21:25606813-25609564~~chr21:25639067-25640965,
chr21:25606813-25609564~~chr21:25707391-25709523,
chr21:25606815-25609560~~chr21:25707341-25710526,
chr21:25606816-25609496~~chr21:25707510-25709485,
chr21:25606818-25609406~~chr21:25707731-25709697,
chr21:25606824-25609539~~chr21:25707688-25710613,
chr21:25606830-25609546~~chr21:25707223-25709539,
chr21:25606834-25609470~~chr21:25707558-25709528,
chr21:25606865-25609546~~chr21:25707695-25710621,
chr21:25606869-25609453~~chr21:25707877-25710598,
chr21:25606871-25609531~~chr21:25707660-25710535,
chr21:25606873-25609559~~chr21:25707322-25709495,
chr21:25606880-25609493~~chr21:25707645-25709314,
chr21:25606885-25609476~~chr21:25707878-25709259,
chr21:25606887-25609611~~chr21:25708003-25709470,
chr21:25606894-25609602~~chr21:25708009-25709440,
chr21:25606899-25609820~~chr21:25639037-25640766,
chr21:25606899-25609820~~chr21:25707427-25709461,
chr21:25606920-25609753~~chr21:25708007-25709432,
chr21:25606927-25609505~~chr21:25708020-25709433,
chr21:25606943-25609746~~chr21:25708004-25709487,
chr21:25606945-25609755~~chr21:25708023-25709409,
chr21:25606952-25609468~~chr21:25707804-25709308,
chr21:25606963-25609577~~chr21:25707939-25710591,
chr21:25606981-25609372~~chr21:25707950-25709246,
chr21:25606981-25609574~~chr21:25707674-25709566,
chr21:25607045-25609461~~chr21:25707835-25709504,
chr21:25607052-25609346~~chr21:25707738-25709299,
chr21:25625000-25650000~~chr21:25725000-25750000,
chr21:25625000-25650000~~chr21:25775000-25800000,
chr21:25625000-25650000~~chr21:26150000-26175000,
chr21:25625000-25650000~~chr21:26825000-26850000,
chr21:25625000-25650000~~chr21:28050000-28075000,
chr21:25650000-25675000~~chr21:26525000-26550000,
chr21:25650000-25675000~~chr21:26925000-26950000,
chr21:25707427-25710615~~chr21:25800672-25802523,
chr21:25707695-25710621~~chr21:25800757-25802438,
- Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET
- Cohesin-loop study:
4DNFIQYQWPF5, GSE95015, 4DNFIDJ2JZ7Q, ENCSR794RDS, ENCSR852KQC, ENCSR361AYD, 4DNFIDSWKFF5, GSE103148, 4DNFI7H4II2V, 4DNFIZ4F74QR, 4DNFIEYQ5ZIR, 4DNFIREVU1Z5, 4DNFIA6NSSBJ, 4DNFIKYXMF1E, GSE99541, ENCSR668RDP, 4DNFIL5K3MA1, GSE97394, 4DNFICEGAHRC, 4DNFI1E6NJQJ, 4DNFI9YAVTI1, ENCSR658RQQ, ENCSR299VMZ, 4DNFIK61ILGM, GSE108869, GSE116872, 4DNFIAWVDQ8C, ENCSR305RTT, ENCSR527RXH, GSE105028, 4DNFIBKZK63V, ENCSR033GUP, 4DNFIQWD8ZYD, 4DNFI3CFMRID, ENCSR662QKG, GSE94872, ENCSR499RVD, 4DNFIB7QTIMH, GSE126792, ENCSR146FPM, ENCSR478BMT, GSE155380, 4DNFIJWBWE41, 4DNFICSTCJQZ, ENCSR587DSF, ENCSR452NHL, 4DNFIIMZB6Y9, GSE80820, GSE52457, Direct, ENCSR314HAC, ENCSR479MTN, 4DNFIAS8LV1C, 4DNFIX7H3CE2, 4DNFIYIAUEPW, ENCSR244BBG, ENCSR991JXX, 4DNFI9815EEJ, 4DNFI9ZWZ5BS, 4DNFIVJ3IIQL, 4DNFIFLJLIS5, 4DNFIDBIEXI7, 4DNFIDZT7PR8, 4DNFIS5F6EBL, 4DNFIZGCA8AH, 4DNFIH7TH4MF, 4DNFIWZEN3FF, ENCSR194SRI, 4DNFI5CGQ46V, 4DNFIE8E4ANZ, GSE120294, 4DNFIPV5KFMK, ENCSR672RHL, 4DNFIW8TIFI5, ENCSR410MDC, 4DNFIMEG1QIC, ENCSR732QOH, 4DNFIBM714BP, 4DNFIF2D3TL9, 4DNFIFHU75I5, 4DNFIYD8LO9Z, ENCSR444BAR, 4DNFIL9M97T2, ENCSR550JLK, 4DNFI3A3VYWU, 4DNFIJ7OAIFQ, 4DNFIALNLR78, 4DNFIYDBBSE3, ENCSR386KHY, 4DNFIEJEFCAM, ENCSR393LOP, GSE44267, 4DNFIPAF4PYT, GSE48592, ENCSR255XYX, ENCSR404HWQ, 4DNFIE5TEYK7, 4DNFIJ8JKKWJ, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, ENCSR933UZH, ENCSR094EIC, GSE58752, GSE116869, 4DNFI8649RQJ, GSE116875, 4DNFIMROE6N4, GSE108787, 4DNFI5SUHCGZ, 4DNFIILDWK8M, ENCSR866FWQ, 4DNFI6EIFUZI, 4DNFII6AN691, ENCSR381DCY, ENCSR981FNA, ENCSR752QCX, ENCSR128RPG, 4DNFI6JJQKFJ, 4DNFI1UEG1HD, GSE101921, ENCSR228TUX, 4DNFI8JFOAJT, 4DNFIOCW5AEM, 4DNFIQVMVRP6, 4DNFIC3HAU11, ENCSR247RGI, ENCSR110JOO, 4DNFI5LCW273, 4DNFINEQY95T, 4DNFIHN2QSMX, 4DNFII84FBKM, 4DNFIVSCH2CH
- Cohesin-loop subunit: SMC1,CTCF,Other,Rad21
- Cohesin-DEGs evidence
- Whether cohesin DEGs: True
-
Involved cell types for DEG evidence: SLK,K-562,Fibroblast,U2OS,CordBlood
- Cohesin-DEGs, number of studies: 5
- Cohesin-DEGs, study: GSE73224,GSE64031,GSE138937,GSE131448,GSE89799
- Cohesin-DEGs, subunit: CTCF,Rad21,SA2,CHOP