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Basic information

CohesinDB ID: CDBP00415264

Locus: chr21-25589610-25591105

Data sourse: GSE103477

Cell type: MDM

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 61% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "5_TxWk": 49%, "4_Tx": 46%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, CBX5, SOX2, NME2, XBP1, FOXA1, LEO1, PBX2, TSC22D4, BMI1, NFIC, RUNX3, PRDM1, CBFB, PAX5, TP63, ZNF736, MAF, ZNF506, ELF1, BCLAF1, SMAD5, ESR1, OCA2, JUN, CTCF, TCF12, EP300, LMO1, GATA6, SIX5, IRF4, POU2F2, CHD8, ZSCAN5D, POU5F1, CDK7, ZNF317, ZBTB48, STAT1, ERG, ASCL1, MYC, RAD21, GRHL3, RXRA, GABPA, STAT3, NKX3-1, VDR, NR3C1, CEBPB, CREB1, SPI1, GATA2, SIX2, FLI1, RUNX1, BCL6, ZFX, MEF2A, ZNF384, NOTCH1, RUNX2, CDK6, ARNT, BACH1, ATF2, PRDM9, FOXM1, PBX3, SUPT5H, FOS, CDK8, PML, MYB, SCRT2, ZNF331, STAT5A, RBM22, BCL11A, TCF3, FOXP1, STAT2, MLLT1, NFATC3, FOXA2, MTA3, CREM, HDAC6, NFATC1, E2F8, PAF1, ZBED1, GTF2B, MEF2C, TCF7, ZBTB33, HOXB13, BCL3, YY1, RELA, TARDBP, JUNB, ZFP36, HIF1A, TCF4, BHLHE22, GATA3, BATF, MAX, ZNF143, ZNF687, PKNOX1, TP53, ZNF334, ELF3, TBX21, AR, TAF1, EGLN2, EGR1, BRD4, SCRT1, AHR

Target gene symbol (double-evidenced CRMs): ATP5PF,JAM2,APP,MRPL39,GABPA

Function elements

Human SNPs: .

Number of somatic mutations (coding): 10

Number of somatic mutations (non-coding): 5

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154721, ENSG00000154723, ENSG00000154727, ENSG00000142192,

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Deatailed information for cohesin site CDBP00415264