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Basic information

CohesinDB ID: CDBP00415218

Locus: chr21-25399514-25400754

Data sourse: ENCSR000BLD, GSE67783, GSE126634, ENCSR000BLY, GSE105028, GSE152721, ENCSR000ECE, GSE206145-NatGen2015, GSE206145, GSE97394

Cell type: RPE, H1-hESC, Fibroblast, HUES64, HSPC, SK-N-SH, HAP1, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.911

Subunit: SA1,Rad21,SA2

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 35% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 86%, "9_Het": 4%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, ZNF467, CHD8, TERF1, ZFX, SP140, XBP1, NOTCH3, OCA2, BRD4, GRHL3, ZBTB48, WT1, SETDB1, TET2, CTCF, SPI1, TFAP2C, EED

Target gene symbol (double-evidenced CRMs): JAM2,APP,ADAMTS1,MRPL39,GABPA,ATP5PF

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154721, ENSG00000154723, ENSG00000154727, ENSG00000142192, ENSG00000154734,

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Deatailed information for cohesin site CDBP00415218