- Basic information
- CohesinDB ID: CDBP00415595
- Locus: chr21-26934483-26934858
-
Data sourse: GSE105028, GSE86191
-
Cell type: HCT-116, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES,Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 62%,
"5_TxWk": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, PGR, POU2F2, FOXA2, MYCN, EZH2phosphoT487, ZSCAN5D, SIN3A, ZFX, POU4F2, XBP1, GTF2B, DUX4, ZBTB48, WT1, FOXA1, TBL1X, TET2, HOXB13, TWIST1, ERG, KDM1A, RELA, ZNF90, ATF3, RUNX2, GATA4, SMARCA4, ISL1, FOXP2, ARNT, CHD7, SP140, HIF1A, POU5F1, GATA3, SMC3, GABPA, SOX11, ZNF143, HAND2, NR3C1, ETV1, TCF7L2, ESR1, KLF9, PITX3, EBF3, PHOX2B, CTCF, BAF155, SPI1, AR, GATA2, ASH2L, NOTCH3, FOXP1, TEAD4, TBX2, PDX1, TFAP2C
- Target gene symbol (double-evidenced CRMs): ADAMTS5,ADAMTS1,JAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 88
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154721,
ENSG00000154734,
ENSG00000154736,
- Related loop:
chr21:17450000-17475000~~chr21:26925000-26950000,
chr21:25650000-25675000~~chr21:26925000-26950000,
chr21:26825000-26850000~~chr21:26925000-26950000,
chr21:26925000-26950000~~chr21:27100000-27125000,
chr21:26925000-26950000~~chr21:27200000-27225000,
chr21:26925000-26950000~~chr21:27300000-27325000,
chr21:26925000-26950000~~chr21:27375000-27400000,
chr21:26925000-26950000~~chr21:27550000-27575000,
chr21:26932823-26934519~~chr21:26951979-26953930,
chr21:26939108-26940527~~chr21:27589432-27591275,