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Basic information

CohesinDB ID: CDBP00415266

Locus: chr21-25595802-25596358

Data sourse: ENCSR000BLD, GSE206145-NatGen2015, GSE103477, GSE68388

Cell type: MDM, H1-hESC, Fibroblast, HuCC-T1

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.956

Subunit: Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 61% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "4_Tx": 55%, "5_TxWk": 43%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: TRP47, POU2F2, SMC1A, FOXA2, POU5F1, E2F7, TOP2A, SOX2, EBF1, PAF1, XBP1, NFATC1, DUX4, GTF2B, ZBTB48, FOXA1, RBFOX2, ERG, RELA, ZNF341, MYC, ZNF362, RAD21, PRDM1, ARNT, GRHL3, SOX11, TAL1, PAX5, TP63, MAF1, ZNF143, SUPT5H, KLF4, SP7, EZH2, OCA2, PHOX2B, CTCF, RBM22, BCL11A, AR, EGLN2, HOXA9, BRD4, SMARCA5, FOXP1, SMC1, ZZZ3, AHR

Target gene symbol (double-evidenced CRMs): GABPA,JAM2,ATP5PF,APP,MRPL39

Function elements

Human SNPs: .

Number of somatic mutations (coding): 20

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154721, ENSG00000154723, ENSG00000154727, ENSG00000142192,

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Deatailed information for cohesin site CDBP00415266