- Basic information
- CohesinDB ID: CDBP00415231
- Locus: chr21-25461860-25462035
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Data sourse: GSE206145
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Cell type: RPE
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 86%,
"5_TxWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CBX5, XBP1, FOXA1, HDGF, TSC22D4, NFIC, RUNX3, CBFB, PAX5, MAF, BCLAF1, SMAD5, USF2, JUN, CTCF, TCF12, EP300, PAX8, DPF2, IRF4, RAD51, RBPJ, EED, POU2F2, MTA2, DUX4, NBN, ARID3A, TBP, MYC, GRHL3, RXRA, BATF3, STAT3, UBN1, IKZF1, CD74, CEBPB, STAT5B, CREB1, SPI1, ZSCAN29, FLI1, DRAP1, RELB, NFYB, SMC1A, BCL6, TRIM22, ZNF18, MEF2A, ZBTB2, ZNF384, ATF2, PRDM9, FOXM1, PBX3, ETV6, FOS, MED1, PML, TERF1, MYB, PIAS1, SMAD1, SETDB1, STAT5A, BCL11A, SP1, NIPBL, REST, ATF7, ASH2L, TCF3, FOXP1, MLLT1, NFATC3, MEF2B, PPARG, FOXA2, MTA3, EBF1, CREM, NFATC1, ZNF207, ZSCAN16, GTF2B, ZBED1, MEF2C, TCF7, BCL3, YY1, RELA, TARDBP, JUNB, TCF4, SKIL, BATF, TAL1, SPIB, NR2F1, ZNF687, PKNOX1, NFKB1, TBX21, BHLHE40, AR, TAF1, ZBTB40, BRD4, AHR
- Target gene symbol (double-evidenced CRMs): JAM2,ATP5PF
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154721,
ENSG00000154723,
- Related loop:
chr21:14525000-14550000~~chr21:25450000-25475000,
chr21:17775000-17800000~~chr21:25450000-25475000,
chr21:25420786-25422730~~chr21:25455832-25458166,
chr21:25423746-25424928~~chr21:25455834-25458451,
chr21:25450000-25475000~~chr21:25550000-25575000,
chr21:25450000-25475000~~chr21:25700000-25725000,
chr21:25450000-25475000~~chr21:29225000-29250000,
chr21:25450000-25475000~~chr21:38225000-38250000,
chr21:25455832-25458166~~chr21:25501013-25503266,
chr21:25455834-25458451~~chr21:25486329-25488255,
chr21:25455834-25458451~~chr21:25572455-25574658,
chr21:25458986-25460259~~chr21:25486634-25488226,