- Basic information
- CohesinDB ID: CDBP00415223
- Locus: chr21-25428548-25429008
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Data sourse: GSE38395, ENCSR000EAC, ENCSR000DZP, GSE206145, ENCSR000BMY, GSE120943, GSE50893
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Cell type: GM12892, Monocytes, GM12878, hLCL, B-cell
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: NIPBL,SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 85%,
"14_ReprPCWk": 10%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, CBX5, ZNF660, SOX2, XBP1, FOXA1, HDGF, TSC22D4, NFIC, CTCFL, RUNX3, PRDM1, CBFB, PAX5, TP63, MAF, ELF1, BCLAF1, TRIM28, KLF6, SNAI2, SMAD5, ESR1, MLL, ZNF217, USF2, CTCF, SND1, TCF12, DPF2, PAX8, IRF4, RAD51, TEAD4, GTF2F1, RBPJ, EED, POU2F2, CHD8, ZSCAN5D, TOP2A, CDK7, MTA2, DUX4, ZBTB48, STAT1, ZNF205, SRF, NBN, ARID3A, ZNF224, TBP, ERG, OGG1, ZNF597, NFKB2, MYC, RAD21, GRHL3, RXRA, NKX2-1, BATF3, GABPA, STAT3, IKZF1, TERF2, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, EZH2, SPI1, IRF1, GATA2, GATAD2B, FLI1, DRAP1, SMARCA5, RELB, RUNX1, BCL6, SMC1A, MAFG, EZH2phosphoT487, AFF4, ZFX, ZNF654, TRIM22, MEF2A, CREBBP, ZNF384, ZBTB2, RUNX2, GATA4, ARNT, PBX4, SOX11, ATF2, PRDM9, ZNF48, ETV6, PBX3, FOXM1, FOS, CDK8, MED1, PML, TERF1, MYB, SMAD1, C11orf30, SETDB1, EVI1, STAT5A, MAFK, BCL11A, NIPBL, SP1, REST, ATF7, ASH2L, HOXA9, TCF3, FOXP1, SMC3, STAT2, MLLT1, STAG1, STAG2, NFATC3, MEF2B, ZNF316, FOXA2, MTA3, EBF1, CREM, NFATC1, ZNF207, MEIS1, E2F8, ZBED1, GTF2B, MEF2C, TCF7, CDK9, HOXB13, BCL3, YY1, RELA, TARDBP, JUNB, BRCA1, SKIL, HIF1A, GATA3, BATF, MAX, SPIB, GATA1, ZNF143, NCOA3, KDM5B, ZNF687, PKNOX1, TP53, MED, ZNF334, NFKB1, PHOX2B, BRD2, ELF3, TBX21, BHLHE40, AR, TAF1, ZBTB40, RB1, IKZF2, BRD4, JUND, SCRT1, ZNF24, AHR
- Target gene symbol (double-evidenced CRMs): ATP5PF,JAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154721,
ENSG00000154723,
- Related loop:
chr21:25400000-25425000~~chr21:25550000-25575000,
chr21:25400000-25425000~~chr21:25575000-25600000,
chr21:25400000-25425000~~chr21:25600000-25625000,
chr21:25400000-25425000~~chr21:25700000-25725000,
chr21:25400000-25425000~~chr21:25725000-25750000,
chr21:25400000-25425000~~chr21:25775000-25800000,
chr21:25400000-25425000~~chr21:26150000-26175000,
chr21:25423746-25424928~~chr21:25455834-25458451,
chr21:25423746-25424928~~chr21:25560899-25563117,
chr21:25425000-25450000~~chr21:25550000-25575000,
chr21:25425000-25450000~~chr21:25700000-25725000,