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Basic information

CohesinDB ID: CDBP00415293

Locus: chr21-25721623-25722022

Data sourse: GSE67783, ENCSR153HNT, GSE86191

Cell type: K-562, HCT-116, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21

CTCF binding site: CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 61% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 54%, "5_TxWk": 42%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: XBP1, FOXA1, RBFOX2, LEO1, TFAP4, HDGF, ZNF362, PRDM1, GLYR1, MECOM, JMJD1C, TRIM28, OCA2, CTCF, TCF12, GATA6, DPF2, ZNF714, TRIM24, POU2F2, CHD8, POU5F1, TOP2A, ZNF317, ZMYND11, ZBTB48, DUX4, DDX5, ERG, ZNF341, MYC, ZNF671, GRHL3, NKX2-1, GABPA, IKZF1, ZNF639, NR3C1, CEBPB, KMT2A, SPI1, HDAC2, GATA2, ZNF777, ZNF554, ETV5, RUNX1, SMC1A, HDAC1, CEBPA, SIN3A, ZFX, ZNF770, PRPF4, ZNF384, GATA4, ZNF184, ARNT, SUPT5H, CHD1, MED1, MYB, SCRT2, NCOA1, TBX5, EVI1, RBM22, BCL11A, NR4A1, ZBTB7A, TCF3, FOXP1, MLLT1, ZNF283, FOXA2, MTA3, PAF1, WT1, MEF2C, HOXB13, RELA, NEUROD1, SP140, HIF1A, GATA1, CEBPG, ZNF334, ZNF366, NOTCH3, BRD4, SCRT1, MAZ, AHR

Target gene symbol (double-evidenced CRMs): JAM2,ATP5PF,MRPL39

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154721, ENSG00000154723,

eachgene

Deatailed information for cohesin site CDBP00415293