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Basic information

CohesinDB ID: CDBP00415512

Locus: chr21-26546651-26547189

Data sourse: GSE103477, GSE101921, ENCSR230ZWH, GSE55407

Cell type: THP-1, Liver, HCAEC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 42% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 69%, "5_TxWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, POU2F2, CHD8, BCL6, ZSCAN5D, CEBPA, SIN3A, ZFX, STAG2, ZSCAN5A, STAT1, ZNF205, MEF2C, ERG, RELA, CREBBP, NOTCH1, ETS1, CHD7, RAD21, ARNT, GRHL3, TCF4, RXRA, HMGB2, GABPA, TAL1, MAX, SPIB, VDR, JMJD1C, CEBPB, NR2F2, TRIM28, KMT2A, ESR1, OCA2, CTCF, TCF12, SP1, SPI1, NR4A1, AR, IRF4, FLI1, NOTCH3, BRD4, SMC1, SMC3, KMT2B, STAG1

Target gene symbol (double-evidenced CRMs): GABPA,MRPL39,JAM2,CYYR1,APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 22

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154721, ENSG00000154727, ENSG00000142192, ENSG00000166265,

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Deatailed information for cohesin site CDBP00415512